Age is just a number: progress and obstacles in the discovery of new candidate drugs for sarcopenia
HJ Kim, DW Jung, DR Williams - Cells, 2023 - mdpi.com
Sarcopenia is a disease characterized by the progressive loss of skeletal muscle mass and
function that occurs with aging. The progression of sarcopenia is correlated with the onset of …
function that occurs with aging. The progression of sarcopenia is correlated with the onset of …
Restoration of epigenetic impairment in the skeletal muscle and chronic inflammation resolution as a therapeutic approach in sarcopenia
G Livshits, A Kalinkovich - Ageing Research Reviews, 2024 - Elsevier
Sarcopenia is an age-associated loss of skeletal muscle mass, strength, and function,
accompanied by severe adverse health outcomes, such as falls and fractures, functional …
accompanied by severe adverse health outcomes, such as falls and fractures, functional …
MuRF‐1 is Involved in Laryngeal Muscle Denervation Atrophy by Regulating G‐Actin Ubiquitination
H Wang, H Wang, X Li, W Xu - The Laryngoscope, 2024 - Wiley Online Library
Objective Muscle RING‐finger protein‐1 (MuRF‐1), an E3 ubiquitin ligase, has been
reported to aggravate skeletal muscle denervated atrophy by mediating the ubiquitination …
reported to aggravate skeletal muscle denervated atrophy by mediating the ubiquitination …
Daidzein improves muscle atrophy caused by lovastatin by regulating the AMPK/FOXO3a axis
K Wang, H Zeng, H Yang - Chinese Medicine, 2024 - Springer
Background Lovastatin, the main lipid-lowering component in red yeast rice, is a golden anti-
lipid drug, but its long-term application is continuously challenged by potential skeletal …
lipid drug, but its long-term application is continuously challenged by potential skeletal …
Muscle-targeted nanoparticles strengthen the effects of small-molecule inhibitors in ameliorating sarcopenia
J Wang, Y He, B Wang, R Yin, B Chen, H Wang - Nanomedicine, 2023 - Taylor & Francis
Background: Sarcopenia is an aging-related degeneration of muscle mass and strength.
Small-molecule inhibitor SW033291 has been shown to attenuate muscle atrophy. Targeted …
Small-molecule inhibitor SW033291 has been shown to attenuate muscle atrophy. Targeted …
[PDF][PDF] 基于灰色GM (1, 1) 模型的2023—2027 年闵行区脑卒中死亡趋势预测
陈林利， 轩水丽， 倪静宜， 郭佳旗， 刘薇， 许慧琳… - 复旦学报(医学 …, 2024 - jms.fudan.edu.cn
目的分析2012—2022 年上海市闵行区脑卒中死亡变化趋势, 预测2023—2027
年脑卒中死亡情况. 方法测算2012—2022 年上海市闵行区脑卒中死亡的年度变化百分比 …
年脑卒中死亡情况. 方法测算2012—2022 年上海市闵行区脑卒中死亡的年度变化百分比 …
肾细胞共培养体系中miR-29b 对OPN/TGF-β 通路的调控作用及高糖环境下该通路的变化.
刘娟， 杨明正， 李肖瑛， 姬婷婷… - … Journal of Medical …, 2024 - search.ebscohost.com
目的建立模拟肾脏屏障系统的肾细胞共培养体系, 探讨miR-29b-3p 对骨桥蛋白(osteopontin,
OPN)/转化生长因子β (transforming growth factor-β, TGF-β) 通路的调控作用及高糖环境下该 …
OPN)/转化生长因子β (transforming growth factor-β, TGF-β) 通路的调控作用及高糖环境下该 …