Enzymes' power for plastics degradation

V Tournier, S Duquesne, F Guillamot… - Chemical …, 2023 - ACS Publications
Plastics are everywhere in our modern way of living, and their production keeps increasing
every year, causing major environmental concerns. Nowadays, the end-of-life management …

Mechanism-based design of efficient PET hydrolases

R Wei, G von Haugwitz, L Pfaff, J Mican… - ACS …, 2022 - ACS Publications
Polyethylene terephthalate (PET) is the most widespread synthetic polyester, having been
utilized in textile fibers and packaging materials for beverages and food, contributing …

[HTML][HTML] Towards bio-upcycling of polyethylene terephthalate

T Tiso, T Narancic, R Wei, E Pollet, N Beagan… - Metabolic …, 2021 - Elsevier
Over 359 million tons of plastics were produced worldwide in 2018, with significant growth
expected in the near future, resulting in the global challenge of end-of-life management. The …

Multiple substrate binding mode-guided engineering of a thermophilic PET hydrolase

L Pfaff, J Gao, Z Li, A Jäckering, G Weber… - ACS …, 2022 - ACS Publications
Thermophilic polyester hydrolases (PES-H) have recently enabled biocatalytic recycling of
the mass-produced synthetic polyester polyethylene terephthalate (PET), which has found …

Complete depolymerization of PET wastes by an evolved PET hydrolase from directed evolution

L Shi, P Liu, Z Tan, W Zhao, J Gao, Q Gu… - Angewandte …, 2023 - Wiley Online Library
PETase displays great potential in PET depolymerization. Directed evolution has been
limited to engineer PETase due to the lack of high‐throughput screening assay. In this study …

Biodegradation of poly (ethylene terephthalate): mechanistic insights, advances, and future innovative strategies

A Kushwaha, L Goswami, M Singhvi, BS Kim - Chemical Engineering …, 2023 - Elsevier
Abstract Globally, poly (ethylene terephthalate)(PET) is the most utilized class of
thermoplastic single-use polyesters, accumulating in ecosystems and aggravating …

Microbial enzymes will offer limited solutions to the global plastic pollution crisis

J Chow, P Perez‐Garcia, R Dierkes… - Microbial …, 2023 - Wiley Online Library
Global economies depend on the use of fossil‐fuel‐based polymers with 360–400 million
metric tons of synthetic polymers being produced per year. Unfortunately, an estimated 60 …

[HTML][HTML] The metabolic potential of plastics as biotechnological carbon sources–review and targets for the future

T Tiso, B Winter, R Wei, J Hee, J de Witt, N Wierckx… - Metabolic …, 2022 - Elsevier
The plastic crisis requires drastic measures, especially for the plastics' end-of-life. Mixed
plastic fractions are currently difficult to recycle, but microbial metabolism might open new …

A comprehensive and critical review on key elements to implement enzymatic PET depolymerization for recycling purposes

A Carniel, V de Abreu Waldow, AM de Castro - Biotechnology Advances, 2021 - Elsevier
Plastics production and recycling chains must be refitted to a circular economy. Poly
(ethylene terephthalate)(PET) is especially suitable for recycling because of its hydrolysable …

Discovering untapped microbial communities through metagenomics for microplastic remediation: recent advances, challenges, and way forward

AK Wani, N Akhtar, N Naqash, F Rahayu… - … Science and Pollution …, 2023 - Springer
Microplastics (MPs) are ubiquitous pollutants persisting almost everywhere in the
environment. With the increase in anthropogenic activities, MP accumulation is increasing …