Maintenance of steady-state mRNA levels by a microRNA-based feed forward loop in the presence of stochastic gene expression noise

I Zabaikina, P Bokes - European Journal of Applied Mathematics, 2024 - cambridge.org
All vital functions of living cells rely on the production of various functional molecules
through gene expression. The production periods are burst-like and stochastic due to the …

Exact and WKB-approximate distributions in a gene expression model with feedback in burst frequency, burst size, and protein stability

P Bokes - bioRxiv, 2020 - biorxiv.org
The expression of individual genes into functional protein molecules is a noisy dynamical
process. Here we model the protein concentration as a jump-drift process which combines …

Hybrid gene expression models

I Zabaikina - iam.fmph.uniba.sk
Regulation of gene expression is represented by a variety of control motifs, mathematical
models of which can provide a theoretical estimate of the process parameters. In this project …