Traditional uses, ten-years research progress on phytochemistry and pharmacology, and clinical studies of the genus Scutellaria

J Shen, P Li, S Liu, Q Liu, Y Li, Y Sun, C He… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Scutellaria (Lamiaceae), which includes
approximately 360–469 accepted species, is widespread in Europe, North America, East …

Plant-derived antioxidants protect the nervous system from aging by inhibiting oxidative stress

X Cui, Q Lin, Y Liang - Frontiers in aging neuroscience, 2020 - frontiersin.org
Alzheimer's disease (AD) has become a major disease contributing to human death and is
thought to be closely related to the aging process. The rich antioxidant substances in plants …

[HTML][HTML] In vitro evaluation of nanoplastics using human lung epithelial cells, microarray analysis and co-culture model

S Yang, Y Cheng, Z Chen, T Liu, L Yin, Y Pu… - … and environmental safety, 2021 - Elsevier
Nanoplastics, including polystyrene nanoplastics (PS-NPs), are widely existed in the
atmosphere, which can be directly and continuously inhaled into the human body, posing a …

Inhibition of oxidative stress and ALOX12 and NF-κB pathways contribute to the protective effect of baicalein on carbon tetrachloride-induced acute liver injury

C Dai, H Li, Y Wang, S Tang, T Velkov, J Shen - Antioxidants, 2021 - mdpi.com
This study investigates the protective effect of baicalein on carbon tetrachloride (CCl4)-
induced acute liver injury and the underlying molecular mechanisms. Mice were orally …

Protective effect of glutathione against oxidative stress-induced cytotoxicity in RAW 264.7 macrophages through activating the nuclear factor erythroid 2-related factor …

DH Kwon, HJ Cha, H Lee, SH Hong, C Park, SH Park… - Antioxidants, 2019 - mdpi.com
Reactive oxygen species (ROS), products of oxidative stress, contribute to the initiation and
progression of the pathogenesis of various diseases. Glutathione is a major antioxidant that …

Metformin attenuates rotenone-induced oxidative stress and mitochondrial damage via the AKT/Nrf2 pathway

N Katila, S Bhurtel, PH Park, DY Choi - Neurochemistry international, 2021 - Elsevier
Oxidative stress and mitochondrial dysfunction are now widely accepted as the major factors
involved in the pathogenesis of Parkinson's disease (PD). Rotenone, a commonly used …

The role of nutritional lifestyle and physical activity in multiple sclerosis pathogenesis and management: a narrative review

S Fanara, M Aprile, S Iacono, G Schirò, A Bianchi… - Nutrients, 2021 - mdpi.com
Studies on the role of nutritional factors and physical activity (PA) in the pathogenesis of
multiple sclerosis (MS) go back a long time. Despite the intrinsic difficulty of studying their …

Molecular targets of brown algae phlorotannins for the therapy of inflammatory processes of various origins

NN Besednova, BG Andryukov, TS Zaporozhets… - Marine Drugs, 2022 - mdpi.com
Inflammatory reactions are part of a complex biological response that plays a vital role in the
appearance of various stimuli resulting from tissue and cell damage, the invasion of …

Methyl Gallate Attenuates Doxorubicin‐Induced Cardiotoxicity in Rats by Suppressing Oxidative Stress

AZ Ahmed, SM Satyam, P Shetty, MR D'Souza - Scientifica, 2021 - Wiley Online Library
Doxorubicin‐induced cardiotoxicity is the leading cause of morbidity and mortality among
cancer survivors. The present study was aimed to investigate the cardioprotective potential …

New Insight on the Cytoprotective/Antioxidant Pathway Keap1/Nrf2/HO-1 Modulation by Ulva intestinalis Extract and Its Selenium Nanoparticles in Rats with …

M Almukainzi, TA El-Masry, H Selim, A Saleh… - Marine Drugs, 2023 - mdpi.com
Currently, there is growing interest in exploring natural bioactive compounds with anti-
inflammatory potential to overcome the side effects associated with the well-known synthetic …