Platelets play a variety of roles in vascular biology and are best recognized as primary
hemostasis and thrombosis mediators. Platelets have a large number of receptors and …

A challenging situation is the association of ITP with pregnancy, which further increases the
risk due to the immunodeficiency of pregnancy, major dangers of bleeding, vital risks for …

Spleen tyrosine kinase (Syk) signaling is central to phagocytosis‐based, antibody‐mediated
platelet destruction in adults with immune thrombocytopenia (ITP). Fostamatinib, an oral Syk …

Primary immune thrombocytopenia (ITP) is an acquired autoimmune bleeding disorder,
characterized by a low platelet count (< 100× 109/L) in the absence of other causes …

Immune thrombocytopenia (ITP) is now well‐known to reduce patients' health‐related
quality of life. However, data describing which signs and symptoms patients and physicians …

MicroRNAs (miRNAs) are small noncoding conserved RNAs containing 19 to 24 nucleotides
that are regulators of post-translational modifications and are involved in the majority of …

Immune thrombocytopenic purpura (ITP) is an autoimmune condition that affects nearly 1:
10,000 people in the world. It is traditionally defined by a platelet count of less than 100 x 10 …

Heavy menstrual bleeding (HMB) is a very common gynecological condition in female
adolescents and a frequent presenting complaint of those with bleeding disorders …

Thrombocytopenia is an often faced problem in the emergency department (ED) that can
signal a life-threatening condition. This situation may be a patient's first presentation of a …

The management of immune thrombocytopenia (ITP) and the prediction of patient response
to therapy still represent a significant and constant challenge in hematology. ITP is a …