Anesthesia and the quantitative evaluation of neurovascular coupling

K Masamoto, I Kanno - Journal of Cerebral Blood Flow & …, 2012 - journals.sagepub.com
Anesthesia has broad actions that include changing neuronal excitability, vascular reactivity,
and other baseline physiologies and eventually modifies the neurovascular coupling …

On the characteristics of functional magnetic resonance imaging of the brain

S Ogawa, RS Menon, SG Kim… - Annual review of …, 1998 - annualreviews.org
▪ Abstract In this review we discuss various recent topics that characterize functional
magnetic resonance imaging (fMRI). These topics include a brief description of MRI image …

Manganese ion enhances T1‐weighted MRI during brain activation: An approach to direct imaging of brain function

YJ Lin, AP Koretsky - Magnetic resonance in medicine, 1997 - Wiley Online Library
Present techniques for functional MRI rely on detecting changes in hemodynamics that
result as a consequence of brain activation. It would be useful if MRI techniques could be …

Functional imaging of the monkey brain

NK Logothetis, H Guggenberger, S Peled… - Nature neuroscience, 1999 - nature.com
Functional magnetic resonance imaging (fMRI) has become an essential tool for studying
human brain function. Here we describe the application of this technique to anesthetized …

Laminar specificity of functional MRI onset times during somatosensory stimulation in rat

AC Silva, AP Koretsky - Proceedings of the National …, 2002 - National Acad Sciences
The blood oxygenation level-dependent (BOLD) response to somatosensory stimulation
was measured in α-chloralose-anesthetized rats. BOLD fMRI was obtained at 40-ms …

Diffusion‐weighted spin‐echo fMRI at 9.4 T: microvascular/tissue contribution to BOLD signal changes

SP Lee, AC Silva, K Ugurbil… - Magnetic Resonance in …, 1999 - Wiley Online Library
The nature of vascular contribution to blood oxygenation level dependent (BOLD) contrast
used in functional MRI (fMRI) is poorly understood. To investigate vascular contributions at …

Functional MRI of calcium‐dependent synaptic activity: cross correlation with CBF and BOLD measurements

TQ Duong, AC Silva, SP Lee… - Magnetic Resonance in …, 2000 - Wiley Online Library
Spatial specificities of the calcium‐dependent synaptic activity, hemodynamic‐based blood
oxygenation level‐dependent (BOLD) and cerebral blood flow (CBF) fMRI were …

A fully noninvasive and robust experimental protocol for longitudinal fMRI studies in the rat

R Weber, P Ramos-Cabrer, D Wiedermann… - Neuroimage, 2006 - Elsevier
Functional magnetic resonance imaging (fMRI) is a unique tool to study brain activity and
plasticity changes. Combination of blood–oxygen level-dependent (BOLD) fMRI and …

Relationship between neural, vascular, and BOLD signals in isoflurane-anesthetized rat somatosensory cortex

K Masamoto, T Kim, M Fukuda, P Wang… - Cerebral cortex, 2007 - academic.oup.com
Functional magnetic resonance imaging (fMRI) in anesthetized rodents has been commonly
performed with α-chloralose, which can be used only for terminal experiments. To develop a …

BOLD study of stimulation-induced neural activity and resting-state connectivity in medetomidine-sedated rat

F Zhao, T Zhao, L Zhou, Q Wu, X Hu - Neuroimage, 2008 - Elsevier
Functional magnetic resonance imaging (fMRI) in anesthetized-animals is critical in studying
the mechanisms of fMRI and investigating animal models of various diseases …