Anticancer properties of capsaicin against human cancer

R Clark, SH Lee - Anticancer research, 2016 - ar.iiarjournals.org
There is persuasive epidemiological and experimental evidence that dietary phytochemicals
have anticancer activity. Capsaicin is a bioactive phytochemical abundant in red and chili …

Mechanisms and clinical uses of capsaicin

SK Sharma, AS Vij, M Sharma - European journal of pharmacology, 2013 - Elsevier
Capsaicin is the active ingredient of chili peppers and gives them the characteristic pungent
flavor. Understanding the actions of capsaicin led to the discovery of its receptor, transient …

A comprehensive review of the carcinogenic and anticarcinogenic potential of capsaicin

K Bley, G Boorman, B Mohammad… - Toxicologic …, 2012 - journals.sagepub.com
Human exposure to capsaicin, the most abundant pungent chili pepper component, is
ubiquitous. Evaluation of capsaicin's carcinogenic potential has produced variable results in …

Biomedical and antioxidant potentialities in chilli: Perspectives and way forward

S Bal, AB Sharangi, TK Upadhyay, F Khan, P Pandey… - Molecules, 2022 - mdpi.com
Worldwide, since ages and nowadays, traditional medicine is well known, owing to its
biodiversity, which immensely contributed to the advancement and development of …

The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile

A Maruca, R Catalano, D Bagetta, F Mesiti… - European journal of …, 2019 - Elsevier
Many bioactive agents have been extracted from plants or belong to functional foods and
have been considered in the treatment of serious and multifactorial diseases, such as …

Capsaicin: friend or foe in skin cancer and other related malignancies?

SR Georgescu, MI Sârbu, C Matei, MA Ilie, C Caruntu… - Nutrients, 2017 - mdpi.com
Capsaicin is the main pungent in chili peppers, one of the most commonly used spices in the
world; its analgesic and anti-inflammatory properties have been proven in various cultures …

Capsaicin induces apoptosis and modulates MAPK signaling in human gastric cancer cells

SY Park, JY Kim, SM Lee, CH Jun… - Molecular …, 2014 - spandidos-publications.com
Capsaicin is known to have tumor suppressive effects. However, the molecular mechanisms
and targets of capsaicin involved in exerting anticancer activity are complex and remain to …

Capsaicin inhibits multiple bladder cancer cell phenotypes by inhibiting tumor-associated NADH oxidase (tNOX) and sirtuin1 (SIRT1)

MH Lin, YH Lee, HL Cheng, HY Chen, FH Jhuang… - Molecules, 2016 - mdpi.com
Bladder cancer is one of the most frequent cancers among males, and its poor survival rate
reflects problems with aggressiveness and chemo-resistance. Recent interest has focused …

Capsaicin: A chili pepper bioactive phytocompound with a potential role in suppressing cancer development and progression

A Mondal, S Banerjee, W Terang… - Phytotherapy …, 2024 - Wiley Online Library
Cancer profoundly influences morbidity and fatality rates worldwide. Patients often have
dismal prognoses despite recent improvements in cancer therapy regimens. However …

[HTML][HTML] Ecto-nOX disulfide-thiol exchanger 2 (ENOX2/tNOX) is a potential prognostic marker in primary malignant melanoma and may serve as a therapeutic target

M Böcker, E Chatziioannou, H Niessner, C Hirn… - International Journal of …, 2024 - mdpi.com
With an increasing incidence of malignant melanoma, new prognostic biomarkers for clinical
decision making have become more important. In this study, we evaluated the role of ecto …