Background Major adverse cardiovascular events (MACE) are increasingly used as
composite outcomes in randomized controlled trials (RCTs) and observational studies …

Abstract Taiwan's National Health Insurance Research Database (NHIRD) exemplifies a
population-level data source for generating real-world evidence to support clinical decisions …

Background Population-level trends in mortality among people with diabetes are
inadequately described. We aimed to examine the magnitude and trends in excess all …

Background/Purpose Taiwan has the highest incidence and prevalence of end-stage kidney
disease (ESKD) worldwide. However, the epidemiologic features of ESKD requiring dialysis …

Importance Few studies have evaluated long-term surgical complications in patients with
prostate cancer (PC) who receive open radical prostatectomy (ORP), laparoscopic radical …

Purpose The validity of the International Classification of Diseases, Tenth Revision, Clinical
Modification (ICD-10-CM) coding for the identification of acute ischemic stroke (AIS) in …

Background We aimed to compare cardiovascular risks among participants with T2DM with
and without subsequent HTN and participants with HTN with and without subsequent T2DM …

Purpose To compile validation findings of diagnosis codes and related algorithms for health
outcomes of interest from National Health Insurance (NHI) or electronic medical records in …

Objective To evaluate the association between recently raised anticholinergic burden and
risk of acute cardiovascular events in older adults. Design Case-case-time-control study (ie …

Background/objective Allergic diseases, such as bronchial asthma, allergic rhinitis, atopic
dermatitis, and psychiatric disorders, are major health issues. There have been reports that …