Medical micro/nanorobots in precision medicine
Advances in medical robots promise to improve modern medicine and the quality of life.
Miniaturization of these robotic platforms has led to numerous applications that leverages …
Miniaturization of these robotic platforms has led to numerous applications that leverages …
Developing biomedical engineering technologies for reproductive medicine
Infertility is a rising global health issue with a far‐reaching impact on the socioeconomic
livelihoods. As there are highly complex causes of male and female infertility, it is highly …
livelihoods. As there are highly complex causes of male and female infertility, it is highly …
Circulating tumor cell isolation, culture, and downstream molecular analysis
S Sharma, R Zhuang, M Long, M Pavlovic, Y Kang… - Biotechnology …, 2018 - Elsevier
Circulating tumor cells (CTCs) are a major contributor of cancer metastases and hold a
promising prognostic significance in cancer detection. Performing functional and molecular …
promising prognostic significance in cancer detection. Performing functional and molecular …
[HTML][HTML] Engineering cancer microenvironments for in vitro 3-D tumor models
The natural microenvironment of tumors is composed of extracellular matrix (ECM), blood
vasculature, and supporting stromal cells. The physical characteristics of ECM as well as the …
vasculature, and supporting stromal cells. The physical characteristics of ECM as well as the …
Microfluidics for sperm analysis and selection
Infertility is a growing global health issue with far-reaching socioeconomic implications. A
downward trend in male fertility highlights the acute need for affordable and accessible …
downward trend in male fertility highlights the acute need for affordable and accessible …
based analytical devices for clinical diagnosis: recent advances in the fabrication techniques and sensing mechanisms
Introduction: There is a significant interest in developing inexpensive portable biosensing
platforms for various applications including disease diagnostics, environmental monitoring …
platforms for various applications including disease diagnostics, environmental monitoring …
Sperm oxidative stress during in vitro manipulation and its effects on sperm function and embryo development
R Gualtieri, G Kalthur, V Barbato, S Longobardi… - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) generated at low levels during mitochondrial respiration
have key roles in several signaling pathways. Oxidative stress (OS) arises when the …
have key roles in several signaling pathways. Oxidative stress (OS) arises when the …
Microfluidic sorting selects sperm for clinical use with reduced DNA damage compared to density gradient centrifugation with swim-up in split semen samples
MM Quinn, L Jalalian, S Ribeiro, K Ona… - Human …, 2018 - academic.oup.com
STUDY QUESTION Does microfluidic sorting improve the selection of sperm with lower DNA
fragmentation over standard density-gradient centrifugation? SUMMARY ANSWER …
fragmentation over standard density-gradient centrifugation? SUMMARY ANSWER …
Sperm quality metrics were improved by a biomimetic microfluidic selection platform compared to swim-up methods
Sperm selection is an essential component of all assisted reproductive treatments (ARTs)
and is by far the most neglected step in the ART workflow in regard to technological …
and is by far the most neglected step in the ART workflow in regard to technological …
Exosomal biomarkers for cancer diagnosis and patient monitoring
Introduction: In recent years, extensive research has been conducted on using exosomes as
biomarkers for cancer detection. Exosomes are 40–150 nm-sized extracellular vesicles …
biomarkers for cancer detection. Exosomes are 40–150 nm-sized extracellular vesicles …