Apigenin is being used by humans in the form of plant extract for the treatment of a number
of disorders and inflammatory conditions, until its discovery as a core compound. Apigenin …

Reactive oxygen species (ROS) are important second messengers in many metabolic
processes and signaling pathways. Disruption of the balance between ROS generation and …

Idiopathic pulmonary fibrosis (IPF) is a progressive, degenerative pulmonary condition.
Transforming growth factor (TGF)-β, platelet-derived growth factor (PDGF), and tumor …

Apigenin is a plant‐derived flavonoid having antiproliferative, anti‐inflammatory, and anti‐
angiogenic properties in chronic and metabolic diseases, and cancers. However, the …

Obesity is a global health problem affecting all age groups, leading to many complications
such as type 2 diabetes, systemic hypertension, cardiovascular disease, dyslipidemia …

Mycotoxins like patulin (PAT) are among the most significant food contaminant with regard to
public health. This study aimed to evaluate the protective effect of apigenin (API), one of the …

Isorhamnetin (ISOR), 3-O-methylquercetin, is a naturally occurring flavonoid in many plants.
It is a metabolite derived from quercetin and is known to exert beneficial effects on the …

Scope Iron deposition is frequently observed in alcoholic liver disease (ALD), which
indicates a potential role of ferroptosis in its development. This study aims to explore the …

ER stress has been implicated in pathophysiological development of many diseases.
Persistent overwhelming stimuli trigger ER stress to initiate apoptosis, autophagy, and cell …

Flavonoid consumption has beneficial effects on human health, however, clinical evidence
remains often inconclusive due to high interindividual variability. Although this high …