Fetal lower urinary tract obstruction (LUTO) is associated with high mortality and postnatal
morbidity caused by lung hypoplasia and impaired kidney function. Specific diagnostic …

Objective Our objective was to evaluate quality of conduct and reporting of published
systematic reviews and meta-analyses in paediatric surgery. We also aimed to identify …

The debate on the use and misuse of P values has risen and fallen throughout their almost
century-long existence in scientific discovery. Over the past few years, the debate has again …

Financial Disclosure Ahmet A. Baschat disclosed receiving royalties from UpToDate. James
J. Cummings disclosed that he receives funding from ONY Biotech, Amherst, NY—first as a …

Cost‐effectiveness analyses (CEA) conducted alongside randomised trials provide key
evidence for informing healthcare decision making, but missing data pose substantive …

Diagnostic ultrasound in obstetrics and gynaecology has experienced a fantastic evolution
during the past seven decades. Initial steps with A-mode technology were followed by B …

Objective To evaluate the ethical and social acceptability of a proposed clinical trial using
maternal uterine artery vascular endothelial growth factor (VEGF) gene therapy to treat …

Fetal lower urinary tract obstruction (LUTO) is a serious condition, which commonly results in
marked perinatal morbidity and mortality. The characteristic prenatal presentation of LUTO …

Fetal surgery is an established but still rapidly evolving specialty, born from the rationale that
destructive embryologic processes, recognized early in gestation, can be curtailed by …

Objectives To assess the spectrum of underlying pathologies, the intrauterine course and
postnatal outcome of 46 fetuses with megacystis that underwent intrauterine vesico-amniotic …