F Citarella, K Takada, P Cascetta, P Crucitti… - Journal of Translational …, 2024 - Springer
Compared to other malignancies, few studies have investigated the role of family history of cancer (FHC) in patients with lung cancer, yielding largely heterogeneous results. We …
Breast cancer (BC) is the leading cause of cancer-related death among women in 2014. Methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR), and MTR …
M Abedinzadeh, M Zare-Shehneh… - Asian Pacific journal …, 2015 - koreascience.kr
Background: The MTHFR C677T polymorphism is a genetic alteration affecting an enzyme involved in folate metabolism, but its relationship to host susceptibility to prostate cancer …
H Al-Shahrani, N Al-Dabbagh, N Al-Dohayan… - BMC …, 2016 - Springer
Background Methylenetetrahydrofolate reductase (MTHFR), a critical enzyme in folate metabolism is involved in DNA synthesis, DNA repair and DNA methylation. The functional …
X Wu, W Xu, T Zhou, N Cao, J Ni, T Zou… - International journal of …, 2016 - mdpi.com
Folate-mediated one-carbon metabolism (FMOCM) is linked to DNA synthesis, methylation, and cell proliferation. Vitamin B6 (B6) is a cofactor, and genetic polymorphisms of related …
Y Yang, LJ Yang, MZ Deng, YY Luo, S Wu, L Xiong… - Genet Mol …, 2016 - funpecrp.com.br
Results from previous studies on the association between methylenetetrahydrofolate reductase (MTHFR) polymorphisms C677T and A1298C and lung cancer have been …
H Ding, Y Wang, Y Chen, C Liu, H Qiu, M Kang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Previous reports implicated 5, 10-ethylenetetrahydrofolate reductase (MTHFR) polymorphisms acted as a potential risk factor for several cancers. In order to explore the …
Рак легкого (РЛ) распространенное онкологическое заболевание и ведущая причина смертности от рака во всем мире. Особенности метаболизма фолатов в организме …
Abstract Purpose 5, 10-Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in folate metabolism and plays a major role in DNA methylation. There are two popular MTHFR …