Elevated glycosylation of CD36 in platelets is a risk factor for oxLDL‐mediated platelet activation in type 2 diabetes
Platelet activation and related cardiovascular complications are the hallmarks of type 2
diabetes (T2D). We investigated the mechanism of platelet activation in T2D using MS …
diabetes (T2D). We investigated the mechanism of platelet activation in T2D using MS …
Characterization and immunogenicity assessment of MERS-CoV pre-fusion spike trimeric oligomers as vaccine immunogen
R Ahuja, P Vishwakarma, S Raj, V Kumar… - Human Vaccines & …, 2024 - Taylor & Francis
Middle East respiratory syndrome coronavirus (MERS-CoV) is a lethal beta-coronavirus that
emerged in 2012. The virus is part of the WHO blueprint priority list with a concerning fatality …
emerged in 2012. The virus is part of the WHO blueprint priority list with a concerning fatality …
In silico analysis and characterization of potential inhibitors of MmaA3, a methoxy mycolic acid synthase from Mycobacterium tuberculosis
B Chaudhary, R Sisodia, D Sarmadhikari… - Journal of …, 2024 - Taylor & Francis
The emergence of the multi-and extensively drug-resistant (MDR and XDR) strains of
Mycobacterium tuberculosis (M. tb), necessitates paradigm-shifting therapeutic approaches …
Mycobacterium tuberculosis (M. tb), necessitates paradigm-shifting therapeutic approaches …
Trypanosomatid DRBD9s are likely to be eIF4B orthologues
Initiation of protein translation is one of the key steps in protein synthesis carried out by
translation initiation factors in conjunction with ribosomes. The roles and mechanisms of …
translation initiation factors in conjunction with ribosomes. The roles and mechanisms of …
Design of 3‐Phenylcoumarins and 3‐Thienylcoumarins as Potent Xanthine Oxidase Inhibitors: Synthesis, Biological Evaluation, and Docking Studies
Coumarin scaffold has proven to be promising in the development of bioactive agents, such
as xanthine oxidase (XO) inhibitors. Novel hydroxylated 3‐arylcoumarins were designed …
as xanthine oxidase (XO) inhibitors. Novel hydroxylated 3‐arylcoumarins were designed …