CM Crosby, M Kronenberg - Nature Reviews Immunology, 2018 - nature.com
Invariant natural killer T cells (iNKT cells) are an innate-like T cell subset that expresses an invariant T cell receptor (TCR) α-chain and recognizes lipids presented on CD1d. They …
Although they are classically viewed as continuously recirculating through the lymphoid organs and blood, lymphocytes also establish residency in non-lymphoid tissues, most …
Invariant natural killer T (iNKT) cells exist in a'poised effector'state, which enables them to rapidly produce cytokines following activation. Using a nearly monospecific T cell receptor …
D Krijgsman, M Hokland, PJK Kuppen - Frontiers in immunology, 2018 - frontiersin.org
Natural killer T (NKT) cells are a subset of CD1d-restricted T cells at the interface between the innate and adaptive immune system. NKT cells can be subdivided into functional …
Y Chen, X Zheng, C Wu - Frontiers in immunology, 2021 - frontiersin.org
Colorectal cancer (CRC) has the second highest mortality rate among all cancers worldwide. Surgery, chemotherapy, radiotherapy, molecular targeting and other treatment …
Natural killer T (NKT) cells are innate-like T cells that rapidly produce a variety of cytokines following T cell receptor (TCR) activation and can shape the immune response in many …
XZ Tang, J Jo, AT Tan, E Sandalova, A Chia… - The Journal of …, 2013 - journals.aai.org
Human mucosal-associated invariant T (MAIT) cells are a T cell population characterized by the expression of a semi-invariant TCR capable of recognizing bacterial products in the …
X Zhou, Y Wang, Z Dou, G Delfanti, O Tsahouridis… - Nature Cancer, 2024 - nature.com
Human natural killer T (NKT) cells have been proposed as a promising cell platform for chimeric antigen receptor (CAR) therapy in solid tumors. Here we generated murine CAR …
M Gaya, P Barral, M Burbage, S Aggarwal, B Montaner… - Cell, 2018 - cell.com
B cells constitute an essential line of defense from pathogenic infections through the generation of class-switched antibody-secreting cells (ASCs) in germinal centers. Although …