Epidemiology of colorectal cancer: incidence, mortality, survival, and risk factors
According to GLOBOCAN 2018 data, colorectal cancer (CRC) is the third most deadly and
fourth most commonly diagnosed cancer in the world. Nearly 2 million new cases and about …
fourth most commonly diagnosed cancer in the world. Nearly 2 million new cases and about …
The new era of cancer immunotherapy: targeting myeloid-derived suppressor cells to overcome immune evasion
P De Cicco, G Ercolano, A Ianaro - Frontiers in immunology, 2020 - frontiersin.org
Suppression of antitumor immune responses is one of the main mechanisms by which tumor
cells escape from destruction by the immune system. Myeloid-derived suppressor cells …
cells escape from destruction by the immune system. Myeloid-derived suppressor cells …
β‐Sitosterol‐assisted silver nanoparticles activates Nrf2 and triggers mitochondrial apoptosis via oxidative stress in human hepatocellular cancer cell line
K Raj R - Journal of biomedical materials research Part A, 2020 - Wiley Online Library
Cancer nanomedicine is an emerging field of cancer therapeutics. Incidence of
hepatocellular carcinoma (HCC) is increasing worldwide, and currently, it is the second …
hepatocellular carcinoma (HCC) is increasing worldwide, and currently, it is the second …
[HTML][HTML] A review of environmental metabolism disrupting chemicals and effect biomarkers associating disease risks: Where exposomics meets metabolomics
J Sun, R Fang, H Wang, DX Xu, J Yang, X Huang… - Environment …, 2022 - Elsevier
Humans are exposed to an ever-increasing number of environmental toxicants, some of
which have gradually been elucidated to be important risk factors for metabolic diseases …
which have gradually been elucidated to be important risk factors for metabolic diseases …
Melatonin in cancer treatment: current knowledge and future opportunities
Melatonin is a pleotropic molecule with numerous biological activities. Epidemiological and
experimental studies have documented that melatonin could inhibit different types of cancer …
experimental studies have documented that melatonin could inhibit different types of cancer …
Breaking the intracellular redox balance with diselenium nanoparticles for maximizing chemotherapy efficacy on patient-derived xenograft models
Excessive oxidative stress in cancer cells can induce cancer cell death. Anticancer activity
and drug resistance of chemotherapy are closely related to the redox state of tumor cells …
and drug resistance of chemotherapy are closely related to the redox state of tumor cells …
Macropinocytosis is an alternative pathway of cysteine acquisition and mitigates sorafenib-induced ferroptosis in hepatocellular carcinoma
Background Macropinocytosis, an important nutrient-scavenging pathway in certain cancer
cells, allows cells to compensate for intracellular amino acid deficiency under nutrient-poor …
cells, allows cells to compensate for intracellular amino acid deficiency under nutrient-poor …
Hepatic stellate cells and hepatocarcinogenesis
Hepatic stellate cells (HSCs) are a significant component of the hepatocellular carcinoma
(HCC) tumor microenvironment (TME). Activated HSCs transform into myofibroblast-like …
(HCC) tumor microenvironment (TME). Activated HSCs transform into myofibroblast-like …
A marine terpenoid, heteronemin, induces both the apoptosis and ferroptosis of hepatocellular carcinoma cells and involves the ROS and MAPK pathways
Hepatocellular carcinoma (HCC) is a leading cause of death, resulting in over 700 thousand
deaths annually worldwide. Chemotherapy is the primary therapeutic strategy for patients …
deaths annually worldwide. Chemotherapy is the primary therapeutic strategy for patients …
Antioxidant role of kaempferol in prevention of hepatocellular carcinoma
N Sharma, S Biswas, N Al-Dayan, AS Alhegaili… - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are noxious to cells because their increased level interacts
with the body's defense mechanism. These species also cause mutations and uncontrolled …
with the body's defense mechanism. These species also cause mutations and uncontrolled …