[HTML][HTML] Biophysical regulation of cell behavior—cross talk between substrate stiffness and nanotopography

Y Yang, K Wang, X Gu, KW Leong - Engineering, 2017 - Elsevier
The stiffness and nanotopographical characteristics of the extracellular matrix (ECM)
influence numerous developmental, physiological, and pathological processes in vivo …

Lineage commitment, signaling pathways, and the cytoskeleton systems in mesenchymal stem cells

AA Saidova, IA Vorobjev - Tissue Engineering Part B: Reviews, 2020 - liebertpub.com
Mesenchymal stem cells (MSCs) from adult tissues are promising candidates for
personalized cell therapy and tissue engineering. Significant progress was achieved in our …

Designing of PLA scaffolds for bone tissue replacement fabricated by ordinary commercial 3D printer

A Gregor, E Filová, M Novák, J Kronek, H Chlup… - Journal of biological …, 2017 - Springer
Background The primary objective of Tissue engineering is a regeneration or replacement of
tissues or organs damaged by disease, injury, or congenital anomalies. At present, Tissue …

Connectivity Map-based discovery of parbendazole reveals targetable human osteogenic pathway

AM Brum, J van de Peppel… - Proceedings of the …, 2015 - National Acad Sciences
Osteoporosis is a common skeletal disorder characterized by low bone mass leading to
increased bone fragility and fracture susceptibility. In this study, we have identified pathways …

Interplay of substrate conductivity, cellular microenvironment, and pulsatile electrical stimulation toward osteogenesis of human mesenchymal stem cells in vitro

G Thrivikraman, PS Lee, R Hess… - … applied materials & …, 2015 - ACS Publications
The influences of physical stimuli such as surface elasticity, topography, and chemistry over
mesenchymal stem cell proliferation and differentiation are well investigated. In this context …

Inhibition of actin polymerization decreases osteogeneic differentiation of mesenchymal stem cells through p38 MAPK pathway

H Sonowal, A Kumar, J Bhattacharyya… - Journal of Biomedical …, 2013 - Springer
Abstract Background Mesenchymal Stem Cells (MSC) are important candidates for
therapeutic applications due to their ex vivo proliferation and differentiation capacity. MSC …

Biodegradable Bicomponent Fibers from Renewable Sources: Melt‐Spinning of Poly(lactic acid) and Poly[(3‐hydroxybutyrate)‐co‐(3‐hydroxyvalerate)]

R Hufenus, FA Reifler… - Macromolecular …, 2012 - Wiley Online Library
PHBV is produced by bacteria as intracellular carbon storage. It is advantageous concerning
biocompatibility and biodegradability, but its low crystallization rate hinders the melt …

Evaluation of biocompatibility using in vitro methods: Interpretation and limitations

A Bruinink, R Luginbuehl - Tissue Engineering III: Cell-Surface Interactions …, 2012 - Springer
The in vitro biocompatibility of novel materials has to be proven before a material can be
used as component of a medical device. This must be done in cell culture tests according to …

Interaction of human osteoblast-like Saos-2 and MG-63 cells with thermally oxidized surfaces of a titanium-niobium alloy

M Vandrovcova, I Jirka, K Novotna, V Lisa, O Frank… - PloS one, 2014 - journals.plos.org
An investigation was made of the adhesion, growth and differentiation of osteoblast-like MG-
63 and Saos-2 cells on titanium (Ti) and niobium (Nb) supports and on TiNb alloy with …

Heterotopic ossification in complex orthopaedic combat wounds: quantification and characterization of osteogenic precursor cell activity in traumatized muscle

TA Davis, FP O'Brien, K Anam, S Grijalva, BK Potter… - JBJS, 2011 - journals.lww.com
Background: Heterotopic ossification frequently develops following high-energy blast
injuries sustained in modern warfare. We hypothesized that differences in the population of …