High bandwidth approaches in nanopore and ion channel recordings-A tutorial review

AJW Hartel, S Shekar, P Ong, I Schroeder, G Thiel… - Analytica Chimica …, 2019 - Elsevier
Transport processes through ion-channel proteins, protein pores, or solid-state nanopores
are traditionally recorded with commercial patch-clamp amplifiers. The bandwidth of these …

[HTML][HTML] Novel α-tubulin mutation disrupts neural development and tubulin proteostasis

MG Hanson, J Aiken, DV Sietsema, D Sept… - Developmental …, 2016 - Elsevier
Mutations in the microtubule cytoskeleton are linked to cognitive and locomotor defects
during development, and neurodegeneration in adults. How these mutations impact …

A reproducible approach to the assembly of microcapillaries for double emulsion production

MA Levenstein, LA Bawazer, CS Mc Nally… - Microfluidics and …, 2016 - Springer
Double emulsions attract considerable interest for their utility in applications as diverse as
drug delivery, contrast agents, and compartmentalizing analytes for fluorescence-activated …

Whole-cell patch-clamp recordings for electrophysiological determination of ion selectivity in channelrhodopsins

C Grimm, J Vierock, P Hegemann, J Wietek - JoVE (Journal of Visualized …, 2017 - jove.com
Over the past decade, channelrhodopsins became indispensable in neuroscientific research
where they are used as tools to non-invasively manipulate electrical processes in target …

[HTML][HTML] Peripheral nervous system defects in a mouse model for peroxisomal biogenesis disorders

MG Hanson, VL Fregoso, JD Vrana, CL Tucker… - Developmental …, 2014 - Elsevier
Peroxisome biogenesis disorders (PBD) are autosomal recessive disorders in humans
characterized by skeletal, eye and brain abnormalities. Despite the fact that neurological …

Characterizing epithelial wound healing in vivo using the cnidarian model organism Clytia hemisphaerica

EEL Lee, E Watto, J Malamy - JoVE (Journal of Visualized Experiments), 2023 - jove.com
All animal organs, from the skin to eyes to intestines, are covered with sheets of epithelial
cells that allow them to maintain homeostasis while protecting them from infection …

3D printing-based frugal manufacturing of glass pipettes for minimally invasive delivery of therapeutics to the brain

G Qiao, D Gulisashvili, A Jablonska, G Zhao… - …, 2023 - mednexus.org
Objective: Intracerebral delivery of agents in liquid form is usually achieved through
commercially available and durable metal needles. However, their size and texture may …

Application of automated image-guided patch clamp for the study of neurons in brain slices

Q Wu, AA Chubykin - JoVE (Journal of Visualized Experiments), 2017 - jove.com
Whole-cell patch clamp is the gold-standard method to measure the electrical properties of
single cells. However, the in vitro patch clamp remains a challenging and low-throughput …

Fire-shaped cylindrical glass micronozzles to measure cell deformability

A Rubio, V Faustino, MG Cabezas… - Journal of …, 2019 - iopscience.iop.org
Most blood cells exhibit a natural deformation capability. Specifically, red blood cells (RBCs)
are characterized by their great ability to deform and squeeze through microcapillary …

Design and fabrication of micromanipulation tools for electrochemical-based manipulation of metal microcomponents

D Li, F Zhang, L Sun, Z Fan - Microsystem Technologies, 2022 - Springer
Micromanipulation tools are the basis for the development of micromanipulation technology.
The problem of reliable, accurate, and non-destructive manipulation of micro-components …