Eph receptors and ephrins in cancer: bidirectional signalling and beyond

EB Pasquale - Nature Reviews Cancer, 2010 - nature.com
The Eph receptor tyrosine kinases and their ephrin ligands have intriguing expression
patterns in cancer cells and tumour blood vessels, which suggest important roles for their …

Heterogeneity of the tumor vasculature

JA Nagy, SH Chang, SC Shih… - … in thrombosis and …, 2010 - thieme-connect.com
The blood vessels supplying tumors are strikingly heterogeneous and differ from their
normal counterparts with respect to organization, structure, and function. Six distinctly …

Long non-coding RNA MALAT1 promotes gastric cancer tumorigenicity and metastasis by regulating vasculogenic mimicry and angiogenesis

Y Li, Z Wu, J Yuan, L Sun, L Lin, N Huang, J Bin, Y Liao… - Cancer letters, 2017 - Elsevier
MALAT1 is an oncogenic long non-coding RNA that has been found to promote the
proliferation of many malignant cell types and non-malignant human umbilical vein …

Vasculogenic mimicry signaling revisited: focus on non-vascular VE-cadherin

D Delgado-Bellido, S Serrano-Saenz… - Molecular cancer, 2017 - Springer
Vasculogenic mimicry (VM) is a blood supply system independent of endothelial vessels in
tumor cells from different origins. It reflects the plasticity of aggressive tumor cells that …

Tumor angiogenesis revisited: regulators and clinical implications

R Ronca, M Benkheil, S Mitola, S Struyf… - Medicinal research …, 2017 - Wiley Online Library
Abstract Since Judah Folkman hypothesized in 1971 that angiogenesis is required for solid
tumor growth, numerous studies have been conducted to unravel the angiogenesis process …

Advanced research on vasculogenic mimicry in cancer

L Qiao, N Liang, J Zhang, J Xie, F Liu… - Journal of cellular …, 2015 - Wiley Online Library
Vasculogenic mimicry (VM) is a brand‐new tumour vascular paradigm independent of
angiogenesis that describes the specific capacity of aggressive cancer cells to form vessel …

[HTML][HTML] Tumor cell vasculogenic mimicry: from controversy to therapeutic promise

REB Seftor, AR Hess, EA Seftor, DA Kirschmann… - The American journal of …, 2012 - Elsevier
In 1999, The American Journal of Pathology published an article entitled “Vascular Channel
Formation by Human Melanoma Cells in Vivo and in Vitro: Vasculogenic Mimicry,” by …

[HTML][HTML] Melanoma: molecular pathogenesis and therapeutic management

Y Liu, MS Sheikh - Molecular and cellular pharmacology, 2014 - ncbi.nlm.nih.gov
Malignant melanoma remains one of the fastest growing cancers worldwide. Although the
primary cutaneous melanoma can be managed by surgery, the advanced metastatic …

Emerging strategies for EphA2 receptor targeting for cancer therapeutics

M Tandon, SV Vemula, SK Mittal - Expert opinion on therapeutic …, 2011 - Taylor & Francis
Importance of the field: High mortality rates with cancers warrant further development of
earlier diagnostics and better treatment strategies. Membrane-bound erythropoietin …

Vasculogenic mimicry, a complex and devious process favoring tumorigenesis–interest in making it a therapeutic target

L Treps, S Faure, N Clere - Pharmacology & therapeutics, 2021 - Elsevier
Tumor cell vasculogenic mimicry (VM), also dubbed vascular mimicry, describes the
plasticity of aggressive cancer cells forming de novo vascular networks and is associated …