Dysregulation of adult hippocampal neuroplasticity in major depression: pathogenesis and therapeutic implications

AN Tartt, MB Mariani, R Hen, JJ Mann… - Molecular psychiatry, 2022 - nature.com
Major depressive disorder (MDD) was previously hypothesized to be a disease of
monoamine deficiency in which low levels of monoamines in the synaptic cleft were …

The transition to motherhood: linking hormones, brain and behaviour

C Servin-Barthet, M Martínez-García, C Pretus… - Nature Reviews …, 2023 - nature.com
We are witnessing a stark increase in scientific interest in the neurobiological processes
associated with pregnancy and maternity. Convergent evidence suggests that around the …

Molecular landscapes of human hippocampal immature neurons across lifespan

Y Zhou, Y Su, S Li, BC Kennedy, DY Zhang, AM Bond… - Nature, 2022 - nature.com
Immature dentate granule cells (imGCs) arising from adult hippocampal neurogenesis
contribute to plasticity and unique brain functions in rodents, and are dysregulated in …

Recent advances on the molecular mechanisms of exercise-induced improvements of cognitive dysfunction

Y Lu, FQ Bu, F Wang, L Liu, S Zhang, G Wang… - Translational …, 2023 - Springer
Physical exercise is of great significance for maintaining human health. Exercise can
provide varying degrees of benefits to cognitive function at all stages of life cycle. Currently …

Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells

D Franjic, M Skarica, S Ma, JI Arellano… - Neuron, 2022 - cell.com
The hippocampal-entorhinal system supports cognitive functions, has lifelong neurogenic
capabilities in many species, and is selectively vulnerable to Alzheimer's disease. To …

Neurogenesis in aging and age-related neurodegenerative diseases

L Culig, X Chu, VA Bohr - Ageing research reviews, 2022 - Elsevier
Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …

Mapping human adult hippocampal neurogenesis with single-cell transcriptomics: reconciling controversy or fueling the debate?

G Tosoni, D Ayyildiz, J Bryois, W Macnair… - Neuron, 2023 - cell.com
The notion of exploiting the regenerative potential of the human brain in physiological aging
or neurological diseases represents a particularly attractive alternative to conventional …

[图书][B] Intentional interviewing and counseling: Facilitating client development in a multicultural society

AE Ivey, MB Ivey, CP Zalaquett - 2018 - thuvienso.hoasen.edu.vn
Copyright 2018 Cengage Learning. All Rights Reserved. May not be copied, scanned, or
duplicated, in whole or in part. WCN 02-2 Page 1 Copyright 2018 Cengage Learning. All …

Early life adversity as a risk factor for cognitive impairment and Alzheimer's disease

Z Huang, JD Jordan, Q Zhang - Translational neurodegeneration, 2023 - Springer
Neurological conditions, including cognitive impairment and Alzheimer's disease (AD),
impose a huge burden on society, affecting millions of people globally. In addition to genetic …

Methods to study adult hippocampal neurogenesis in humans and across the phylogeny

J Terreros‐Roncal, M Flor‐García… - …, 2023 - Wiley Online Library
The hippocampus hosts the continuous addition of new neurons throughout life—a
phenomenon named adult hippocampal neurogenesis (AHN). Here we revisit the …