Cardiovascular diseases (CVDs) are one of the primary causes of mortality worldwide. An
optimal mitochondrial function is central to supplying tissues with high energy demand, such …

Mitochondrial diseases are a large class of human hereditary diseases, accompanied by the
dysfunction of mitochondria and the disruption of cellular energy synthesis, that affect …

Hypertrophic cardiomyopathy (HCM) is the most prominent cause of sudden cardiac death
in young people. Due to heterogeneity in clinical manifestations, conventional HCM drugs …

Cardiac disease is still the leading cause of morbidity and mortality worldwide, despite some
exciting and innovative improvements in clinical management. In particular, atrial fibrillation …

Mitochondrial Cardiomyopathy (MCM) is a common manifestation of multi-organ
Mitochondrial Diseases (MDs), occasionally present in non-syndromic cases. Diagnosis of …

BACKGROUND Mutations in mitochondrial tRNA (mt-tRNA) genes that result in
mitochondrial dysfunction play important roles in type 2 diabetes mellitus (T2DM). We pre …

The mitochondrial-derived peptides (MDPs) are a new class of small open reading frame
encoded polypeptides with pleiotropic properties. The prominent members are Humanin …

Hypertrophic cardiomyopathy (HCM) is a heart condition characterized by cellular and
metabolic dysfunction, with mitochondrial dysfunction playing a crucial role. Although the …

RNA editing is widely involved in stem cell differentiation and development; however, RNA
editing events during human cardiomyocyte differentiation have not yet been characterized …

Abstract Ambient fine particle (PM 2.5) is one of the potential risk factors for the
cardiovascular disease, which is characterized by a marked shift in energy substrate …