Gamma-Mobile-Trio systems are mobile elements rich in bacterial defensive and offensive tools

T Mahata, K Kanarek, MG Goren… - Nature …, 2024 - nature.com
The evolutionary arms race between bacteria and phages led to the emergence of bacterial
immune systems whose diversity and dynamics remain poorly understood. Here we use …

Pipolins are bimodular platforms that maintain a reservoir of defense systems exchangeable with various bacterial genetic mobile elements

V Mateo-Cáceres… - Nucleic Acids Research, 2024 - academic.oup.com
Defense genes gather in diverse types of genomic islands in bacteria and provide immunity
against viruses and other genetic mobile elements. Here, we disclose pipolins, previously …

A widespread bacterial mobile genetic element encodes weapons against phages, bacteria, and eukaryotes

T Mahata, K Kanarek, MG Goren, E Bosis, U Qimron… - bioRxiv, 2023 - biorxiv.org
Bacteria are found in ongoing conflicts with rivals and predators, which lead to an
evolutionary arms race and the development of innate and adaptive immune systems …

A novel strategy to protect prokaryotic cells from virus infection

Y Ishino - Engineering Microbiology, 2024 - Elsevier
The recent discovery of the CRISPR-Cas-mediated acquired immunity system highlights the
fact that our knowledge of phage/virus defense mechanisms encoded in bacterial and …