Adult haemophagocytic syndrome

M Ramos-Casals, P Brito-Zerón, A López-Guillermo… - The Lancet, 2014 - thelancet.com
Haemophagocytic syndromes (haemophagocytic lymphohistiocytosis) have a wide range of
causes, symptoms, and outcomes, but all lead to a hyperinflammatory response and organ …

Hemophagocytic lymphohistiocytosis: review of etiologies and management

MR George - Journal of blood medicine, 2014 - Taylor & Francis
Hemophagocytic lymphohistiocytosis (HLH) covers a wide array of related life-threatening
conditions featuring ineffective immunity characterized by an uncontrolled …

Familial and acquired hemophagocytic lymphohistiocytosis

GE Janka - Annual review of medicine, 2012 - annualreviews.org
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome in which an
uncontrolled and ineffective immune response, triggered in most cases by infectious agents …

Hemophagocytic lymphohistiocytosis: an update on diagnosis and pathogenesis

FGN Rosado, AS Kim - American journal of clinical pathology, 2013 - academic.oup.com
Hemophagocytic lymphohistiocytosis (HLH) is a frequently fatal and likely underdiagnosed
disease involving a final common pathway of hypercytokinemia, which can result in end …

Clinical features of cytokine storm syndrome

M Shimizu - Cytokine storm syndrome, 2019 - Springer
The common clinical features of cytokine storm syndrome (CSS) are sustained fever,
splenomegaly, hepatomegaly with liver dysfunction, lymphadenopathy, coagulopathy …

A consensus review on malignancy‐associated hemophagocytic lymphohistiocytosis in adults

N Daver, K McClain, CE Allen, SA Parikh, Z Otrock… - Cancer, 2017 - Wiley Online Library
Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of severe immune activation and
dysregulation resulting in extreme and often life‐threatening inflammation. HLH has been …

Hemophagocytic syndromes—an update

GE Janka, K Lehmberg - Blood reviews, 2014 - Elsevier
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory
syndrome and not an independent disease. HLH represents the extreme end of a severe …

Clinical features of haemophagocytic syndrome in patients with systemic autoimmune diseases: analysis of 30 cases

S Fukaya, S Yasuda, T Hashimoto, K Oku… - …, 2008 - academic.oup.com
Objectives. Haemophagocytic syndrome (HPS) is known as a relatively rare complication in
autoimmune diseases. Here we analysed the clinical features of HPS in patients with …

Pulmonary involvement in patients with hemophagocytic lymphohistiocytosis

A Seguin, L Galicier, D Boutboul, V Lemiale, E Azoulay - Chest, 2016 - Elsevier
Background Acquired hemophagocytic lymphohistiocytosis (HLH) is a life-threatening event
that usually occurs as a complication of immunodeficiency. Lung involvement in HLH has …

[HTML][HTML] Current status of the diagnosis and treatment of hemophagocytic lymphohistiocytosis in adults

YR Kim, DY Kim - Blood research, 2021 - synapse.koreamed.org
Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of defective apoptosis, a
disruption of the regulatory pathway that terminates immune and inflammatory responses …