The BMP pathway and its inhibitors in the skeleton

JW Lowery, V Rosen - Physiological reviews, 2018 - journals.physiology.org
Bone morphogenetic proteins (BMPs) constitute the largest subdivision of the transforming
growth factor-β family of ligands. BMPs exhibit widespread utility and pleiotropic, context …

Relationship between metabolic syndrome and bone health–an evaluation of epidemiological studies and mechanisms involved

KY Chin, SK Wong, SO Ekeuku… - … , Metabolic Syndrome and …, 2020 - Taylor & Francis
Metabolic syndrome (MetS) and osteoporosis are two medical problems plaguing the
ageing populations worldwide. Though seemingly distinctive to each other, metabolic …

Defective S‐TiO2−x/CeO2 Heterojunction for Mutual Reinforcing Chemodynamic/Sonocatalytic Antibacterial Therapy and Sonoelectric/Ion‐Activated Bone …

C Wang, J Lei, C Mao, S Wu, Y Zheng… - Advanced Functional …, 2023 - Wiley Online Library
Sonocatalysis and chemodynamics have attracted widespread attention in antibacterial
therapy. The transfer efficiency of electrons plays an important role in sonocatalysis and …

[HTML][HTML] BMP signaling in mesenchymal stem cell differentiation and bone formation

M Beederman, JD Lamplot, G Nan, J Wang… - Journal of biomedical …, 2013 - ncbi.nlm.nih.gov
Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily and have
diverse functions during development and organogenesis. BMPs play a major role in …

Ablation of fat cells in adult mice induces massive bone gain

W Zou, N Rohatgi, JR Brestoff, Y Li, RA Barve… - Cell metabolism, 2020 - cell.com
Adipocytes control bone mass, but the mechanism is unclear. To explore the effect of
postnatal adipocyte elimination on bone cells, we mated mice expressing an inducible …

Functional Comparison of Chronological and In Vitro Aging: Differential Role of the Cytoskeleton and Mitochondria in Mesenchymal Stromal Cells

S Geißler, M Textor, J Kühnisch, D Könnig, O Klein… - PloS one, 2012 - journals.plos.org
Mesenchymal stromal cells (MSCs) are of high relevance for the regeneration of
mesenchymal tissues such as bone and cartilage. The promising role of MSCs in cell-based …

Polycaprolactone nanofiber scaffold enhances the osteogenic differentiation potency of various human tissue-derived mesenchymal stem cells

R Xue, Y Qian, L Li, G Yao, L Yang, Y Sun - Stem cell research & therapy, 2017 - Springer
Background Polycaprolactone (PCL) has been regarded as a promising synthetic material
for bone tissue engineering application. Owing to its unique biochemical properties and …

A 3D printable and bioactive hydrogel scaffold to treat traumatic brain injury

L Che, Z Lei, P Wu, D Song - Advanced Functional Materials, 2019 - Wiley Online Library
Traumatic brain injury accompanied by intracranial hypertension remains one of the most
fatal injuries worldwide. Usually, patients must undergo two surgeries, craniectomy and …

[HTML][HTML] MicroRNAs regulate signaling pathways in osteogenic differentiation of mesenchymal stem cells

S Peng, D Gao, C Gao, P Wei… - Molecular medicine …, 2016 - spandidos-publications.com
Osteogenesis is a complex multi-step process involving the differentiation of mesenchymal
stem cells (MSCs) into osteoblast progenitor cells, preosteoblasts, osteoblasts and …

[HTML][HTML] The pathogenesis of ossification of the posterior longitudinal ligament

L Yan, R Gao, Y Liu, B He, S Lv, D Hao - Aging and disease, 2017 - ncbi.nlm.nih.gov
Ossification of the posterior longitudinal ligament (OPLL) is a multi-factorial disease
involving an ectopic bone formation of spinal ligaments. It affects 0.8-3.0% aging Asian and …