V András, J Tomek, N Nagy, L Virág… - Physiological …, 2021 - journals.physiology.org
Cardiac arrhythmias are among the leading causes of mortality. They often arise from alterations in the electrophysiological properties of cardiac cells and their underlying ionic …
S Joukar - Laboratory Animal Research, 2021 - Springer
Electrocardiogram (ECG) is a non-invasive valuable diagnostic tool that is used in clinics for investigation and monitoring of heart electrical rhythm/conduction, ischemia/injury of heart …
DJ Blackwell, J Schmeckpeper… - Circulation research, 2022 - Am Heart Assoc
Cardiac arrhythmias are a significant cause of morbidity and mortality worldwide, accounting for 10% to 15% of all deaths. Although most arrhythmias are due to acquired heart disease …
JC Hancox, CY Du, A Butler… - … of the Royal …, 2023 - royalsocietypublishing.org
The congenital short QT syndrome (SQTS) is a rare condition characterized by abbreviated rate-corrected QT (QTc) intervals on the electrocardiogram and by increased susceptibility to …
Cardiac arrhythmias are a major cause of death and disability. A large number of experimental cell and animal models have been developed to study arrhythmogenic …
A Shiti, G Arbil, N Shaheen, I Huber, N Setter… - Journal of Molecular and …, 2023 - Elsevier
Background Among the monogenic inherited causes of atrial fibrillation is the short QT syndrome (SQTS), a rare channelopathy causing atrial and ventricular arrhythmias. One of …
B Asatryan, L Yee, Y Ben-Haim, S Dobner… - Circulation, 2021 - Am Heart Assoc
Sex-related differences in prevalence, clinical presentation, and outcome of cardiac channelopathies are increasingly recognized, despite their autosomal transmission and …
Z Selimi, JS Rougier, H Abriel… - The Journal of …, 2023 - Wiley Online Library
Cardiac voltage‐gated sodium (Na+) channels (Nav1. 5) are crucial for myocardial electrical excitation. Recent studies based on single‐channel recordings have suggested that Na+ …
BACKGROUND: Despite major advances in the clinical management of long QT syndrome, some patients are not fully protected by beta-blocker therapy. Mexiletine is a well-known …