Hierarchical nanomaterials assembled from peptoids and other sequence-defined synthetic polymers

Z Li, B Cai, W Yang, CL Chen - Chemical Reviews, 2021 - ACS Publications
In nature, the self-assembly of sequence-specific biopolymers into hierarchical structures
plays an essential role in the construction of functional biomaterials. To develop synthetic …

The design and biomedical applications of self-assembled two-dimensional organic biomaterials

X Zhang, C Gong, OU Akakuru, Z Su, A Wu… - Chemical Society …, 2019 - pubs.rsc.org
The design and applications of some inorganic two-dimensional (2D) nanomaterials such as
graphene, graphyne, and borophene have been widely studied in recent years. Meanwhile …

Single-molecule polypeptoid stretching reveals the effects of charge sequence on chain conformation

HP Truong, S Mengel, B Yu, RA Segalman… - …, 2023 - ACS Publications
Elucidating the effect of charge sequence on polyelectrolyte conformation is important to
understanding many biophysical processes and advancing the design of sequence-defined …

Glycosylated peptoid nanosheets as a multivalent scaffold for protein recognition

A Battigelli, JH Kim, DC Dehigaspitiya, C Proulx… - ACS …, 2018 - ACS Publications
Glycoproteins adhered on the cellular membrane play a pivotal role in a wide range of
cellular functions. Their importance is particularly relevant in the recognition process …

Discovery of stable and selective antibody mimetics from combinatorial libraries of polyvalent, loop-functionalized peptoid nanosheets

JH Kim, SC Kim, MA Kline, EM Grzincic, BW Tresca… - ACS …, 2019 - ACS Publications
The ability of antibodies to bind a wide variety of analytes with high specificity and high
affinity makes them ideal candidates for therapeutic and diagnostic applications. However …

Nanotubes, plates, and needles: pathway-dependent self-assembly of computationally designed peptides

Y Tian, FB Polzer, HV Zhang, KL Kiick… - …, 2018 - ACS Publications
Computationally designed peptides form desired antiparallel, tetrameric coiled-coil bundles
that hierarchically assemble into a variety of well-controlled nanostructures depending on …

Engineering the atomic structure of sequence-defined peptoid polymers and their assemblies

S Xuan, RN Zuckermann - Polymer, 2020 - Elsevier
Peptoids are a family of sequence-defined, non-natural biomimetic polymers which show
excellent properties including good chemical and enzymatic stability and high structural …

Uniform, large-area, highly ordered peptoid monolayer and bilayer films for sensing applications

DJ Murray, JH Kim, EM Grzincic, SC Kim, AR Abate… - Langmuir, 2019 - ACS Publications
The production of atomically defined, uniform, large-area 2D materials remains as a
challenge in materials chemistry. Many methods to produce 2D nanomaterials suffer from …

Synthetic CO2-fixation enzyme cascades immobilized on self-assembled nanostructures that enhance CO2/O2 selectivity of RubisCO

S Satagopan, Y Sun, JR Parquette, FR Tabita - Biotechnology for biofuels, 2017 - Springer
Background With increasing concerns over global warming and depletion of fossil-fuel
reserves, it is attractive to develop innovative strategies to assimilate CO 2, a greenhouse …

Design and preparation of organic nanomaterials using self‐assembled peptoids

A Battigelli - Biopolymers, 2019 - Wiley Online Library
The self‐assembly and self‐organization of peptoids, peptidomimetic polymers composed of
N‐substituted glycine monomers, can result in a plethora of well‐defined organic …