Pathogenicity and virulence regulation of Vibrio cholerae at the interface of host-gut microbiome interactions
ABSTRACT The Gram-negative bacterium Vibrio cholerae is responsible for the severe
diarrheal pandemic disease cholera, representing a major global public health concern …
diarrheal pandemic disease cholera, representing a major global public health concern …
Breathing life into pathogens: the influence of oxygen on bacterial virulence and host responses in the gastrointestinal tract
B Marteyn, FB Scorza, PJ Sansonetti… - Cellular …, 2011 - Wiley Online Library
The gastrointestinal tract provides a variety of environmental challenges to any bacterium
seeking to successfully colonize or cause disease in a host. A major obstacle is the varied …
seeking to successfully colonize or cause disease in a host. A major obstacle is the varied …
Bicarbonate Induces Vibrio cholerae Virulence Gene Expression by Enhancing ToxT Activity
BH Abuaita, JH Withey - Infection and immunity, 2009 - Am Soc Microbiol
Vibrio cholerae is a gram-negative bacterium that is the causative agent of cholera, a severe
diarrheal illness. The two biotypes of V. cholerae O1 capable of causing cholera, classical …
diarrheal illness. The two biotypes of V. cholerae O1 capable of causing cholera, classical …
The LysR-Type Virulence Activator AphB Regulates the Expression of Genes in Vibrio cholerae in Response to Low pH and Anaerobiosis
G Kovacikova, W Lin, K Skorupski - Journal of bacteriology, 2010 - Am Soc Microbiol
AphB is a LysR-type activator that initiates the expression of the virulence cascade in Vibrio
cholerae by cooperating with the quorum-sensing-regulated activator AphA at the tcpPH …
cholerae by cooperating with the quorum-sensing-regulated activator AphA at the tcpPH …
Vibrio cholerae anaerobic induction of virulence gene expression is controlled by thiol-based switches of virulence regulator AphB
Z Liu, M Yang, GL Peterfreund… - Proceedings of the …, 2011 - National Acad Sciences
Bacterial pathogens have evolved sophisticated signal transduction systems to coordinately
control the expression of virulence determinants. For example, the human pathogen Vibrio …
control the expression of virulence determinants. For example, the human pathogen Vibrio …
Adaptation of Vibrio cholerae to Hypoxic Environments
Bacteria can colonize virtually any environment on Earth due to their remarkable capacity to
detect and respond quickly and adequately to environmental stressors. Vibrio cholerae is a …
detect and respond quickly and adequately to environmental stressors. Vibrio cholerae is a …
The highly variable microbiota associated to intestinal mucosa correlates with growth and hypoxia resistance of sea bass, Dicentrarchus labrax, submitted to different …
FJ Gatesoupe, C Huelvan, N Le Bayon, H Le Delliou… - BMC microbiology, 2016 - Springer
Background The better understanding of how intestinal microbiota interacts with fish health
is one of the key to sustainable aquaculture development. The present experiment aimed at …
is one of the key to sustainable aquaculture development. The present experiment aimed at …
The crystal structure of AphB, a virulence gene activator from Vibrio cholerae, reveals residues that influence its response to oxygen and pH
JL Taylor, RS De Silva, G Kovacikova, W Lin… - Biophysical …, 2012 - cell.com
University of Illinois at Urbana-Champaign, Urbana, IL, USA. The muscleblind-like protein 1
(MBNL1) is an RNA binding protein that regulates mRNA alternative splicing. It is implicated …
(MBNL1) is an RNA binding protein that regulates mRNA alternative splicing. It is implicated …
The Entner-Doudoroff pathway is obligatory for gluconate utilization and contributes to the pathogenicity of Vibrio cholerae
ABSTRACT The Entner-Doudoroff (ED) pathway has recently been shown to play an
important role in sugar catabolism for many organisms although very little information is …
important role in sugar catabolism for many organisms although very little information is …
A Genome-Wide Approach to Discovery of Small RNAs Involved in Regulation of Virulence in Vibrio cholerae
ES Bradley, K Bodi, AM Ismail, A Camilli - PLoS pathogens, 2011 - journals.plos.org
Small RNAs (sRNAs) are becoming increasingly recognized as important regulators in
bacteria. To investigate the contribution of sRNA mediated regulation to virulence in Vibrio …
bacteria. To investigate the contribution of sRNA mediated regulation to virulence in Vibrio …