Mesenchymal stem cells (MSCs) have been used in clinic for approximately 20 years.
During this period, various new populations of MSCs have been found or manipulated …

Background Distraction osteogenesis (DO) is a functional tissue engineering approach that
applies gradual mechanical traction on the bone tissues after osteotomy to stimulate bone …

Mesenchymal stem cells have awakened a great deal of interest in regenerative medicine
due to their plasticity, and immunomodulatory and anti-inflammatory properties. They are …

Chronic musculoskeletal (MSK) pain is one of the most common medical complaints
worldwide and musculoskeletal injuries have an enormous social and economical impact …

Mesenchymal stem cells (MSCs) are capable of differentiating into multilineage cells, thus
making them a significant prospect as a cell source for regenerative therapy; however, the …

Atherosclerosis (AS) is a chronic inflammatory disease of arteries fueled by lipids. It is a
major cause of cardiovascular morbidity and mortality. Mesenchymal stem cells have been …

Bone defects may impede normal biomechanics and the structural stability of bone as an
organ. In many cases, the correction of bone defects requires extensive surgical intervention …

Continued improvements in the understanding and application of mesenchymal stem cells
(MSC) have revolutionized tissue engineering. This is particularly true within the field of …

Introduction: Cell-based therapies exploit the heterogeneous and self-sufficient biological
environment of stem cells to restore, maintain and improve tissue functions. Adipose-derived …

Bone is one of the most dynamic tissues in the human body that can heal following injury
without leaving a scar. However, in instances of extensive bone loss, this intrinsic capacity of …