Oral microbiota in human systematic diseases

X Peng, L Cheng, Y You, C Tang, B Ren, Y Li… - International journal of …, 2022 - nature.com
Oral bacteria directly affect the disease status of dental caries and periodontal diseases. The
dynamic oral microbiota cooperates with the host to reflect the information and status of …

Autoantibodies and B Cells: The ABC of rheumatoid arthritis pathophysiology

M Volkov, KA van Schie… - Immunological …, 2020 - Wiley Online Library
Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation. In
the last few decades, new insights into RA‐specific autoantibodies and B cells have greatly …

From rheumatoid factor to anti-citrullinated protein antibodies and anti-carbamylated protein antibodies for diagnosis and prognosis prediction in patients with …

CY Wu, HY Yang, SF Luo, JH Lai - International Journal of Molecular …, 2021 - mdpi.com
Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease mainly involving
synovial inflammation and articular bone destruction. RA is a heterogeneous disease with …

The role of the oral microbiome in the development of diseases

M Kozak, A Pawlik - International Journal of Molecular Sciences, 2023 - mdpi.com
Periodontal disease (PD) is a complex and infectious illness that begins with a disruption of
bacterial homeostasis. This disease induces a host inflammatory response, leading to …

The COVID-19 Global Rheumatology Alliance: collecting data in a pandemic

PC Robinson, J Yazdany - Nature Reviews Rheumatology, 2020 - nature.com
The global COVID-19 pandemic has the potential to severely affect those with rheumatic
diseases or who are taking immunosuppressive therapies. Information is lacking as to how …

PAD enzymes in rheumatoid arthritis: pathogenic effectors and autoimmune targets

AM Curran, P Naik, JT Giles, E Darrah - Nature Reviews Rheumatology, 2020 - nature.com
Peptidylarginine deiminases (PADs) have an important role in the pathogenesis of
rheumatoid arthritis (RA) owing to their ability to generate citrullinated proteins—the …

Insights into peptidylarginine deiminase expression and citrullination pathways

K Yu, P Proost - Trends in Cell Biology, 2022 - cell.com
Peptidylarginine deiminases (PADs) are calcium-dependent enzymes that mediate
citrullination, an irreversible post-translational modification (PTM). PAD enzymes have …

[HTML][HTML] Periodontitis and periodontopathic bacteria as risk factors for rheumatoid arthritis: A review of the last 10 years

T Kobayashi, PM Bartold - Japanese Dental Science Review, 2023 - Elsevier
Rheumatoid arthritis (RA) is characterized by chronic inflammatory destruction of joint tissue
and is caused by an abnormal autoimmune response triggered by interactions between …

Bacterial extracellular vesicles and their interplay with the immune system

E Doré, E Boilard - Pharmacology & Therapeutics, 2023 - Elsevier
The mammalian intestinal tract harbors trillions of microorganisms confined within this space
by mucosal barriers. Despite these barriers, bacterial components may still be found …

Virulence and Pathogenicity Properties of Aggregatibacter actinomycetemcomitans

GN Belibasakis, T Maula, K Bao, M Lindholm… - Pathogens, 2019 - mdpi.com
Aggregatibacter actinomycetemcomitans is a periodontal pathogen colonizing the oral cavity
of a large proportion of the human population. It is equipped with several potent virulence …