In situ gelling formulations are drug delivery systems which typically exist in a liquid form at
room temperature and change into gel state after application to the body in response to …

Although the oral route is the most convenient route for drug administration, there are a
number of circumstances where this is not possible from either a clinical or pharmaceutical …

Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal
epithelial surface, and mucin molecules and increase the residence time of the dosage form …

Nasal drug delivery has now been recognized as a very promising route for delivery of
therapeutic compounds including biopharmaceuticals. It has been demonstrated that low …

Drug delivery via the rectum is a useful alternative route of administration to the oral route for
patients who cannot swallow. Traditional rectal dosage forms have been historically used for …

Bioadhesion can be defined as the process by which a natural or a synthetic polymer can
adhere to a biological substrate. When the biological substrate is a mucosal layer then the …

Mucoadhesive drug delivery systems stick to mucosal tissues and prolong the local retention
time of drugs. Since the colon is covered by a mucosal layer, mucoadhesive rectal …

Conventional ophthalmic solutions often eliminate rapidly after administration and cannot
provide and maintain an adequate concentration of the drug in the precorneal area. To solve …

Liquid suppository systems composed of poloxamers and bioadhesive polymers were easy
to administer to the anus and mucoadhesive to the rectal tissues without leakage after the …

This study described the thermosensitive formulations composed of poloxamer mixtures for
use as drug delivery platform via mucosal route. It also characterized the poloxamer …