Protein–protein interactions (PPIs) drive biological processes, and disruption of PPIs can
cause disease. With recent breakthroughs in structure prediction and a deluge of genomic …

Two-component flavin-dependent enzymes are abundant in nature and are involved in a
wide variety of biological reactions. These enzymes consist of a reductase which generates …

Protein–protein interactions (PPIs) are pivotal for driving diverse biological processes, and
any disturbance in these interactions can lead to disease. Thus, the study of PPIs has been …

Interaction sites on protein surfaces mediate virtually all biological activities, and their
identification holds promise for disease treatment and drug design. Novel algorithmic …

The neuronal-voltage gated sodium channel (VGSC), NaV1. 6, plays an important role in
propagating action potentials along myelinated axons. Calmodulin (CaM) is known to …

Immunodominant membrane protein (IMP) is a prevalent membrane protein in phytoplasma
and has been confirmed to be an F-actin-binding protein. However, the intricate molecular …

Toll-like receptor 4 (TLR4), a pattern recognition receptor, is activated by
lipopolysaccharides (LPS) and induces the MyD88 pathway, which subsequently produces …

Most proteins function within networks and, therefore, protein interactions are central to
protein function. Although stable macromolecular machines have been extensively studied …

Eukaryotic cells coordinate available nutrients with their growth through the mechanistic
target of rapamycin complex 1 (mTORC1) pathway, in which numerous evolutionarily …

Calor (Erwärmung), Tumor (Schwellung), Dolor (Schmerz) und Functio Laesa (
Funktionseinschränkung)[20]. Die ersten Zellen, die dabei in das Gewebe auswandern, um …