Risk for Alzheimer's disease (AD) is associated with age-related loss of sex steroid
hormones in both women and men. In post-menopausal women, the precipitous depletion of …

Nuclear receptors are ligand-activated transcription factors and include the receptors for
steroid hormones, lipophilic vitamins, sterols, and bile acids. These receptors serve as …

Structure−Activity Relationship for Thiohydantoin Androgen Receptor Antagonists for
Castration-Resistant Prostate Cancer (CRPC) | Journal of Medicinal Chemistry ACS ACS …

A promising strategy to delay and perhaps prevent Alzheimer's disease (AD) is to identify the
age-related changes that put the brain at risk for the disease. A significant normal age …

Selective androgen receptor modulators as function promoting... : Current Opinion in Clinical
Nutrition & Metabolic Care Selective androgen receptor modulators as function promoting …

Many xenobiotics have been associated with endocrine effects in a wide range of biological
systems. These associations are usually between small nonsteroid molecules and steroid …

Interest in the development and therapeutic potential of nonsteroidal tissue-selective
androgen receptor modulators (SARMs) a has increased dramatically within the past …

The androgen receptor (AR) is transcriptionally activated by high affinity binding of
testosterone (T) or its 5α-reduced metabolite, dihydrotestosterone (DHT), a more potent …

Androgen receptor (AR) plays a critical role in the function of several organs including
primary and accessory sexual organs, skeletal muscle, and bone, making it a desirable …

Despite significant advances in contraceptive options for women over the last 50 yr, world
population continues to grow rapidly. Scientists and activists alike point to the devastating …