Understanding the rules of life is one of the most important scientific endeavours and has
revolutionised both biology and biotechnology. Remarkable advances in observation …

It has been estimated that over a billion dollars in resources can be consumed to obtain
clinical approval, and only a few new chemical entities are approved by the US Food and …

Cyan variants of green fluorescent protein are widely used as donors in Förster resonance
energy transfer experiments. The popular, but modestly bright, Enhanced Cyan Fluorescent …

Monitoring neuronal electrical activity using fluorescent protein-based voltage sensors has
been limited by small response magnitudes and slow kinetics of existing probes. Here we …

Nr4a receptors are activated by T cell receptor (TCR) signaling and play key roles in T cell
differentiation. Which TCR signaling pathways regulate Nr4a receptors and their sensitivities …

Nanothermometry methods with intracellular sensitivities have the potential to make
important contributions to fundamental cell biology and medical fields, as temperature is a …

Smart gels have a variety of applications, including tissue engineering and controlled drug
delivery. Here we present a modular, bottom-up approach that permits the creation of protein …

Fluorescent proteins are now a critical tool in all areas of biomedical research. In this article,
we review the techniques required to use fluorescent proteins for flow cytometry …

Microalgal chloroplasts, such as those of the model organism Chlamydomonas reinhardtii,
are emerging as a new platform to produce recombinant proteins, including industrial …

Recent advancements in single cell sequencing technologies allow for identification of
numerous immune-receptors expressed by T cells such as tumor-specific and autoimmune T …