The SLC6A15–SLC6A20 Neutral Amino Acid Transporter Subfamily: Functions, Diseases, and Their Therapeutic Relevance

J Kukułowicz, K Pietrzak-Lichwa, K Klimończyk… - Pharmacological …, 2024 - Elsevier
The neutral amino acid transporter subfamily that consists of six members, consecutively
SLC6A15–SLC620, also called orphan transporters, represents membrane, sodium …

Genetic justification of COVID‐19 patient outcomes using DERGA, a novel data ensemble refinement greedy algorithm

PG Asteris, AH Gandomi, DJ Armaghani… - Journal of Cellular …, 2024 - Wiley Online Library
Complement inhibition has shown promise in various disorders, including COVID‐19. A
prediction tool including complement genetic variants is vital. This study aims to identify …

Role of the Neanderthal Genome in Genetic Susceptibility to COVID-19: 3p21. 31 Locus in the Spotlight

M Yaghmouri, P Izadi - Biochemical Genetics, 2024 - Springer
Since the outbreak of COVID-19, genome-wide association studies have tried to discover
the role of genetic predisposition in the clinical variability of this viral infection. The findings …

Molecular Profile of Variants Potentially Associated with Severe Forms of COVID-19 in Amazonian Indigenous Populations

RCC Coelho, CLLP Martins, LF Pastana… - Viruses, 2024 - mdpi.com
Coronavirus disease 2019 (COVID-19) is an infection caused by SARS-CoV-2. Genome-
wide association studies (GWASs) have suggested a strong association of genetic factors …

Genomic investigation on genes related to mercury metabolism in Amazonian indigenous populations

VHV Carvalho, JCG Rodrigues, LWMS Vinagre… - Science of The Total …, 2024 - Elsevier
Studies have identified elevated levels of mercury in Amazonian Indigenous individuals,
highlighting them as one of the most exposed to risks. In the unique context of the Brazilian …

Pharmacogenomic Profile of Amazonian Amerindians

JCG Rodrigues, MR Fernandes… - Journal of Personalized …, 2022 - mdpi.com
Given the role of pharmacogenomics in the large variability observed in drug efficacy/safety,
an assessment about the pharmacogenomic profile of patients prior to drug prescription or …

Molecular Profile of Important Genes for Radiogenomics in the Amazon Indigenous Population

MC de Lima, CC de Castro, KEC Aguiar… - Journal of Personalized …, 2024 - mdpi.com
Radiotherapy is focused on the tumor but also reaches healthy tissues, causing toxicities
that are possibly related to genomic factors. In this context, radiogenomics can help reduce …

[HTML][HTML] Risk factors for COVID-19 mortality in hospitalized patients in Bolivia

J Limachi-Choque, J Guitian, C Leyns… - IJID regions, 2023 - Elsevier
Objectives This study aimed to ascertain which factors are associated with higher risk of
mortality among hospitalized COVID-19 Bolivian patients. Methods This retrospective …

Host Genetic Variants Linked to COVID-19 Neurological Complications and Susceptibility in Young Adults—A Preliminary Analysis

A Kazantseva, R Enikeeva, Z Takhirova… - Journal of Personalized …, 2023 - mdpi.com
To date, multiple efforts have been made to use genome-wide association studies (GWAS)
to untangle the genetic basis for SARS-CoV-2 infection susceptibility and severe COVID-19 …

[HTML][HTML] Modelling flock heterogeneity in the transmission of peste des petits ruminants virus and its impact on the effectiveness of vaccination for eradication

B Savagar, BA Jones, M Arnold, M Walker, G Fournié - Epidemics, 2023 - Elsevier
Peste des petits ruminants (PPR) is an acute infectious disease of small ruminants targeted
for global eradication by 2030. The Global Strategy for Control and Eradication (GSCE) …