Three theories of regeneration dominate neuroscience today, all purporting to explain why
the adult central nervous system (CNS) cannot regenerate. One theory proposes that Nogo …

Adult neurogenesis consists in the generation of newborn neurons from neural stem cells
taking place in the adult brain. In mammals, this process is limited to very few areas of the …

Neurogenesis involves generation of new neurons through finely tuned multistep processes,
such as neural stem cell (NSC) proliferation, migration, differentiation, and integration into …

BACKGROUND: Ankyrin 3 (ANK3) has been strongly implicated as a risk gene for bipolar
disorder (BD) by recent genome-wide association studies of patient populations. However …

The neuropeptide VGF (non-acronymic), which has antidepressant-like effects, enhances
adult hippocampal neurogenesis as well as synaptic activity and plasticity in the …

Background Early life stress is thought to contribute to psychiatric disorders, but the precise
mechanisms underlying this link are poorly understood. As neonatal stress decreases adult …

Adult hippocampal neurogenesis is an important process in the regulation of cognition,
stress responsivity, and sensitivity to antidepressant and mood stabiliser drugs. Increasing …

The mood stabilizers lithium, valproate and lamotrigine are traditionally used to treat bipolar
disorder. However, accumulating evidence suggests that these drugs have broad …

Glucagon‐like peptide‐1 (GLP‐1) is derived from the processing of proglucagon in intestinal
L‐cells and releases insulin from pancreatic β‐cells as an incretin. The GLP‐1 receptor has …

Hippocampal neurogenesis plays a very important role in learning and memory functions. In
a search for best neurological drugs that protect neuronal cells and stimulate neurogenesis …