Metabolic-Dysfunction-Associated Steatotic Liver Disease—Its Pathophysiology, Association with Atherosclerosis and Cardiovascular Disease, and Treatments

H Yanai, H Adachi, M Hakoshima, S Iida… - International journal of …, 2023 - mdpi.com
Metabolic-dysfunction-associated steatotic liver disease (MASLD) is a chronic liver disease
that affects more than a quarter of the global population and whose prevalence is increasing …

Unraveling Mechanisms of Genetic Risks in Metabolic Dysfunction–Associated Steatotic Liver Diseases: A Pathway to Precision Medicine

X Zhang, KM Chang, J Yu… - Annual Review of …, 2025 - annualreviews.org
Metabolic dysfunction–associated steatotic liver disease (MASLD) is a growing global health
problem, affecting∼ 1 billion people. This condition is well established to have a heritable …

Lactiplantibacillus plantarum FRT4 attenuates high-energy low-protein diet-induced fatty liver hemorrhage syndrome in laying hens through regulating gut-liver axis

D Li, H Cai, G Liu, Y Han, K Qiu, W Liu, K Meng… - Journal of Animal …, 2024 - Springer
Background Fatty liver hemorrhage syndrome (FLHS) becomes one of the most major
factors resulting in the laying hen death for caged egg production. This study aimed to …

A coding variant in the microsomal triglyceride transfer protein reduces both hepatic steatosis and plasma lipids

CV Schneider, L Hehl, KT Creasy… - Alimentary …, 2023 - Wiley Online Library
Background Genetic inactivation and pharmacologic inhibition of the microsomal triglyceride
transfer protein (MTP; gene name MTTP) inhibits hepatic secretion of VLDL, thereby …

The contribution of genetics and epigenetics to MAFLD susceptibility

V Moretti, S Romeo, L Valenti - Hepatology International, 2024 - Springer
Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most common liver
disease worldwide. The risk of developing MAFLD varies among individuals, due to a …

Crosstalk between Epigenetics and Metabolic Reprogramming in Metabolic Dysfunction-Associated Steatotic Liver Disease-Induced Hepatocellular Carcinoma: A …

A Li, R Wang, Y Zhao, P Zhao, J Yang - Metabolites, 2024 - mdpi.com
Epigenetic and metabolic reprogramming alterations are two important features of tumors,
and their reversible, spatial, and temporal regulation is a distinctive hallmark of …

[HTML][HTML] Association between serum perfluoroalkyl substances concentrations and non-alcoholic fatty liver disease among Korean adults: a cross-sectional study …

YT Park, EY Chung, CH Chae… - Annals of Occupational and …, 2024 - ncbi.nlm.nih.gov
Background Perfluoroalkyl substances (PFAS) are widely used in industry and daily life due
to their useful properties. They have a long half-life, accumulate in the body, and there is …

Hepatic steatosis and its associations with acute and chronic liver diseases

AB Koenig, A Tan, H Abdelaal, F Monge… - Alimentary …, 2024 - Wiley Online Library
Background Hepatic steatosis is a common finding in liver histopathology and the hallmark
of metabolic dysfunction‐associated steatotic liver disease (MASLD), formerly known as non …