Inflammatory processes in alzheimer's disease—pathomechanism, diagnosis and treatment: a review

B Twarowski, M Herbet - International journal of molecular sciences, 2023 - mdpi.com
Alzheimer's disease is one of the most commonly diagnosed cases of senile dementia in the
world. It is an incurable process, most often leading to death. This disease is multifactorial …

Astrocytes as a therapeutic target in alzheimer's disease–comprehensive review and recent developments

M Rodríguez-Giraldo, RE González-Reyes… - International Journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is a frequent and disabling neurodegenerative disorder, in which
astrocytes participate in several pathophysiological processes including neuroinflammation …

Microglia and astrocyte involvement in neurodegeneration and brain cancer

AA Vandenbark, H Offner, S Matejuk… - Journal of …, 2021 - Springer
The brain is unique and the most complex organ of the body, containing neurons and
several types of glial cells of different origins and properties that protect and ensure normal …

Astrocytes and the psychiatric sequelae of COVID-19: What we learned from the pandemic

L Steardo Jr, L Steardo, C Scuderi - Neurochemical Research, 2023 - Springer
COVID-19, initially regarded as specific lung disease, exhibits an extremely broad spectrum
of symptoms. Extrapulmonary manifestations of the disease also include important …

Reactive and senescent astroglial phenotypes as hallmarks of brain pathologies

A Lazic, V Balint, D Stanisavljevic Ninkovic… - International Journal of …, 2022 - mdpi.com
Astrocytes, as the most abundant glial cells in the central nervous system, are tightly
integrated into neural networks and participate in numerous aspects of brain physiology and …

Cholesterol dysmetabolism in Alzheimer's disease: a starring role for astrocytes?

E Staurenghi, S Giannelli, G Testa, B Sottero… - Antioxidants, 2021 - mdpi.com
In recent decades, the impairment of cholesterol metabolism in the pathogenesis of
Alzheimer's disease (AD) has been intensively investigated, and it has been recognized to …

Morphological connectivity differences in Alzheimer's disease correlate with gene transcription and cell‐type

H Yu, Y Ding, Y Wei, M Dyrba, D Wang… - Human brain …, 2023 - Wiley Online Library
Alzheimer's disease (AD) is one of the most prevalent forms of dementia in older individuals.
Convergent evidence suggests structural connectome abnormalities in specific brain …

Pharmacological considerations for treating neuroinflammation with curcumin in Alzheimer's disease

X Zhou, M Venigalla, R Raju, G Münch - Journal of Neural Transmission, 2022 - Springer
Abstract Prof. Dr. Peter Riederer, the former Head of the Neurochemistry Department of the
Psychiatry and Psychotherapy Clinic at the University of Würzburg (Germany), has been one …

Co-ultramicronized palmitoylethanolamide/luteolin restores oligodendrocyte homeostasis via peroxisome proliferator-activated receptor-α in an in vitro model of …

R Facchinetti, M Valenza, C Gomiero, GF Mancini… - Biomedicines, 2022 - mdpi.com
Oligodendrocytes are cells fundamental for brain functions as they form the myelin sheath
and feed axons. They perform these critical functions thanks to the cooperation with other …

[HTML][HTML] The identification of a distinct astrocyte subtype that diminishes in Alzheimer's disease

H Wei, J Withrow, J Rakshit, FU Amin… - Aging and …, 2024 - pmc.ncbi.nlm.nih.gov
Alzheimer's disease (AD) is characterized by the presence of two hallmark pathologies: the
accumulation of Amyloid beta (Aβ) and tau proteins in the brain. There is a growing body of …