Objective: Measurement-based care involves the systematic administration of symptom
rating scales and use of the results to drive clinical decision making at the level of the …

AimsBipolar disorder (BD) is a severe psychiatric disorder associated with a high risk of
suicide. This meta-analysis examined the prevalence of suicide attempts (SA) in patients …

BACKGROUND: Early onset of mood symptoms in bipolar disorder has been associated
with poor outcome in many studies; however, the factors that might contribute to poor …

Background Episodes of depression are the most frequent cause of disability among
patients with bipolar disorder. The effectiveness and safety of standard antidepressant …

OBJECTIVE: Little is known about clinical features associated with the risk of recurrence in
patients with bipolar disorder receiving treatment according to contemporary practice …

This introductory article to the special edition on glutamate neurotransmission in
neuropsychiatric disorders provides an overview of glutamate neurotransmitter system …

Background Bipolar patients are at risk for relapses of their illness even when undergoing
optimal pharmacotherapy. This study was performed to determine whether combining family …

We performed a genome-wide association scan in 1461 patients with bipolar (BP) 1
disorder, 2008 controls drawn from the Systematic Treatment Enhancement Program for …

OBJECTIVE: The authors provide a detailed perspective on the correlates of comorbid
anxiety in a large, well-characterized sample of bipolar disorder patients. METHOD: Anxiety …

Context Psychosocial interventions have been shown to enhance pharmacotherapy
outcomes in bipolar disorder. Objective To examine the benefits of 4 disorder-specific …