Migrasome: a new functional extracellular vesicle

X Zhang, L Yao, Y Meng, B Li, Y Yang, F Gao - Cell Death Discovery, 2023 - nature.com
Migrasome is a novel cellular organelle produced during cell migration, and its biogenesis
depends on the migration process. It is generated in a variety of cells such as immune cells …

Blood protein biomarkers in lung cancer

H Huang, Y Yang, Y Zhu, H Chen, Y Yang, L Zhang… - Cancer Letters, 2022 - Elsevier
Lung cancer has consistently ranked first as the cause of cancer-associated mortality. The 5-
year survival rate has risen slowly, and the main obstacle to improving the prognosis of …

Unignored intracellular journey and biomedical applications of extracellular vesicles

J Zhao, W Zhu, Y Mao, X Li, G Ling, C Luo… - Advanced Drug Delivery …, 2024 - Elsevier
The intracellular journey of extracellular vesicles (EVs) cannot be ignored in various
biological pathological processes. In this review, the biogenesis, biological functions, uptake …

The endothelium and COVID-19: an increasingly clear link brief title: endotheliopathy in COVID-19

I Six, N Guillaume, V Jacob, R Mentaverri… - International Journal of …, 2022 - mdpi.com
The endothelium has a fundamental role in the cardiovascular complications of coronavirus
disease 2019 (COVID-19). Infection with severe acute respiratory syndrome coronavirus 2 …

Exosomes in brain diseases: Pathogenesis and therapeutic targets

Q Si, L Wu, D Pang, P Jiang - MedComm, 2023 - Wiley Online Library
Exosomes are extracellular vesicles with diameters of about 100 nm that are naturally
secreted by cells into body fluids. They are derived from endosomes and are wrapped in …

[HTML][HTML] Exosomes and ultrasound: the future of theranostic applications

B Sridharan, HG Lim - Materials Today Bio, 2023 - Elsevier
Biomaterials and pertaining formulations have been very successful in various diagnostic
and therapeutic applications because of its ability to overcome pharmacological limitations …

Diagnostic and prognostic role of extracellular vesicles in pancreatic cancer: current evidence and future perspectives

A Nicoletti, M Negri, M Paratore, F Vitale… - International Journal of …, 2023 - mdpi.com
Pancreatic cancer is one of the most aggressive tumors, with a dismal prognosis due to poor
detection rates at early stages, rapid progression, post-surgical complications, and limited …

The Increasing Diagnostic Role of Exosomes in Inflammatory Diseases to Leverage the Therapeutic Biomarkers

Y Wang, H Ma, X Zhang, X Xiao… - Journal of Inflammation …, 2024 - Taylor & Francis
Inflammatory diseases provide substantial worldwide concerns, affecting millions of people
and healthcare systems by causing ongoing discomfort, diminished quality of life, and …

Extracellular Vesicles: Novel Potential Therapeutic Agents in Inflammatory Bowel Diseases

I Mignini, G Piccirilli, F Termite, M Paratore, G Esposto… - Cells, 2023 - mdpi.com
Patients affected by inflammatory bowel diseases (IBD) can nowadays benefit from a
growing number of pharmacological options. However, in moderate-to-severe cases, the …

Defects in exosome biogenesis are associated with sensorimotor defects in zebrafish vps4a mutants

A Shipman, Y Gao, D Liu, S Sun, J Zang… - Journal of …, 2024 - jneurosci.org
Mutations in human VPS4A are associated with neurodevelopmental defects, including
motor delays and defective muscle tone. VPS4A encodes a AAA-ATPase required for …