The CT Colonography Reporting and Data System (C-RADS) has withstood the test of time
and proven to be a robust classification scheme for CT colonography (CTC) findings. C …

Histopathological characterization of colorectal polyps allows to tailor patients' management
and follow up with the ultimate aim of avoiding or promptly detecting an invasive carcinoma …

Background The phenomenon of field cancerization reflects the transition of normal cells
into those predisposed to cancer. Assessing the scope and intensity of this process in the …

Twenty-five percent of cervical cancers are classified as endocervical adenocarcinomas
(EACs), which comprise a highly heterogeneous group of tumors. A histopathologic risk …

McKittrick–Wheelock syndrome commonly presents with a triad of chronic secretory
diarrhea, electrolyte disturbances, and renal failure. Secretory diarrhea is due to active ion …

Tubular adenomas (TA) are the most frequent of all colorectal adenomas. Current definitions
of TA do not include the phenotype of the dysplastic crypts. We report a novel crypt …

Colorectal cancer (CRC) is one of the few cancers that have an established dysplasia-
carcinoma sequence that benefits from screening. Everyone over 50 years of age in Canada …

Descriptions of the various dysplastic crypt phenotypes occurring in TA have remained
unattended in the literature. Recently, new crypt-phenotypes, characterized by crypt rings in …

Due to the high incidence of colorectal cancer worldwide, the underlying molecular
mechanisms have been extensively investigated. The Wnt/β‑catenin signaling pathway …

Purpose The aim of this study is to develop an effective approach for differentiating between
hyperplastic and tubular adenoma colon polyps, which is one of the most difficult tasks in …