Pluripotent stem cells (PSCs) hold great promise for drug discovery and regenerative
medicine owing to their ability to differentiate into any cell type in the body. After more than …

Abstract Expression of microRNA (miR)-126 is enriched in endothelial cells (ECs) and
endothelial progenitor cells (EPCs). MiR-126 is considered a master regulator of …

The use of human pluripotent stem cells for in vitro disease modelling and clinical
applications requires protocols that convert these cells into relevant adult cell types. Here …

The blood-brain barrier (BBB) is crucial to the health of the brain and is often compromised
in neurological disease. Moreover, because of its barrier properties, this endothelial …

Human pluripotent stem cell (hPSC)-derived endothelial cells and their progenitors may
provide the means for vascularization of tissue-engineered constructs and can serve as …

Objective—Stem cell therapy for angiogenesis and vascular regeneration has been
investigated using adult or embryonic stem cells. In the present study, we investigated the …

Objective—Endothelial cells (ECs), pericytes, and vascular smooth muscle cells (vSMCs)
are essential for vascular development, and their dysfunction causes multiple cardiovascular …

A number of challenges in skin grafting for wound healing have drawn researchers to focus
on skin tissue engineering as an alternative solution. The core idea of tissue engineering is …

One of the greatest examples of integrated signal transduction is revealed by examination of
effects mediated by AKT kinase in myocardial biology. Positioned at the intersection of …

Impaired or damaged blood vessels can occur at all levels in the hierarchy of vascular
systems from large vasculatures such as arteries and veins to meso‐and microvasculatures …