Krüppel-like factor 4 (KLF4) is an evolutionarily conserved zinc finger-containing
transcription factor that regulates diverse cellular processes such as cell growth …

Both hereditary and sporadic breast cancer are suggested to develop from a stem cell
subcomponent retaining most key stem cell properties but with dysregulation of self-renewal …

The Krüppel-like factor (KLF) family of transcription factors regulates diverse biological
processes that include proliferation, differentiation, growth, development, survival, and …

Sp1-like proteins and Krüppel-like factors (KLFs) are highly related zinc-finger proteins that
are important components of the eukaryotic cellular transcriptional machinery. By regulating …

Abstract Kruppel-like factor 4 (KLF4) is highly expressed in more than 70% of breast cancers
and functions as an oncogene. However, an exact mechanism by which KLF4 enhances …

The Sp/KLF family contains at least twenty identi® ed members which include Sp1-4 and
numerous kruÈppel-like factors. Members of the family bind with varying af® nities to …

The number of available breast cancer cell (BCC) lines is small, and only a very few of them
have been extensively studied. Whether they are representative of the tumours from which …

The combined activity of three transcription factors can reprogram adult cells into induced
pluripotent stem cells (iPSCs). However, the transgenic methods used for delivering …

Generating pluripotent stem cells directly from cells obtained from patients is one of the
ultimate goals in regenerative medicine. Two" reprogramming" strategies for the generation …

Abstract KLF4 (GKLF/EZF) encodes a transcription factor that is associated with both tumour
suppression and oncogenesis. We describe the identification of KLF4 in a functional …