AIEgens for microbial detection and antimicrobial therapy

H Bai, W He, JHC Chau, Z Zheng, RTK Kwok… - Biomaterials, 2021 - Elsevier
Pathogenic microbes can cause infections or diseases in hosts and they pose ongoing
threats to human health. Antibiotics have been taken an active role in treating a wide variety …

AIEgens for microorganism‐related visualization and therapy

Z Ye, W He, Z Zhang, Z Qiu, Z Zhao… - Interdisciplinary …, 2023 - Wiley Online Library
Humans and bacteria have always been closely related. However, pathogenic bacteria and
drug‐resistant bacteria pose a certain threat to human life and health. On the other hand …

The role of structural hydrophobicity on cationic amphiphilic aggregation-induced emission photosensitizer-bacterial interaction and photodynamic efficiency

MMS Lee, EY Yu, D Yan, JHC Chau, Q Wu, JWY Lam… - ACS …, 2023 - ACS Publications
The aggregation-induced emission photosensitizer (AIE PS) has stood out as an alternative
and competent candidate in bacterial theranostics, particularly with the use of cationic AIE …

Double‐pronged antimicrobial agents based on a donor‐π‐acceptor type aggregation‐induced emission luminogen

Y Wu, J Li, Z Shen, D Wang, R Dong… - Angewandte …, 2022 - Wiley Online Library
Novel antibacterial agents are urgently needed to control the infections induced by multidrug‐
resistant (MDR) bacteria. Herein, we rationally designed and facilely synthesized a new D‐π …

AIEgen-loaded nanofibrous membrane as photodynamic/photothermal antimicrobial surface for sunlight-triggered bioprotection

M Li, H Wen, H Li, ZC Yan, Y Li, L Wang, D Wang… - Biomaterials, 2021 - Elsevier
The outbreak of infectious diseases such as COVID-19 causes an urgent need for abundant
personal protective equipment (PPE) which leads to a huge shortage of raw materials …

Lysosome-targeting aggregation-induced emission nanoparticle enables adoptive macrophage transfer-based precise therapy of bacterial infections

P Wang, B Wu, M Li, Y Song, C Chen, G Feng, D Mao… - ACS …, 2023 - ACS Publications
Traditional antibacterial procedures are getting inefficient due to the emergence of
antimicrobial resistance, which makes alternative treatments in urgent demand. However …

Recent advances in hypoxia‐overcoming strategy of aggregation‐induced emission photosensitizers for efficient photodynamic therapy

H Chen, Y Wan, X Cui, S Li… - Advanced Healthcare …, 2021 - Wiley Online Library
Hypoxia is an inherent physiologic barrier in the microenvironment of solid tumor and has
badly restricted the therapeutic effect of photodynamic therapy (PDT). Meanwhile, the …

A NIR-II emissive polymer AIEgen for imaging-guided photothermal elimination of bacterial infection

Y Huang, D Li, D Wang, X Chen, L Ferreira… - Biomaterials, 2022 - Elsevier
The development of antibiotics resistance has made multidrug-resistant (MDR) bacterial
infection one of the most serious global health issues. Photothermal therapy (PTT) is an …

Nanomaterial-based strategies in antimicrobial applications: Progress and perspectives

Y Zhao, L Chen, Y Wang, X Song, K Li, X Yan, L Yu… - Nano Research, 2021 - Springer
The dramatic increase of microbial resistances against conventional available antibiotics is
a huge challenge to the effective treatment of infectious disease and thus becoming a …

Incorporating spin-orbit coupling promoted functional group into an enhanced electron DA system: A useful designing concept for fabricating efficient photosensitizer …

Z Yang, Z Zhang, Y Sun, Z Lei, D Wang, H Ma, BZ Tang - Biomaterials, 2021 - Elsevier
Intersystem crossing (ISC) is of great significance in photochemistry, and has a decisive
influence on the properties of photosensitizers (PSs) for use in photodynamic therapy (PDT) …