Mechanotransduction couples mechanical stimulation with ion flux, which is critical for
normal biological processes involved in neuronal cell development, pain sensation, and red …

Mechanotransduction, the conversion of physical forces into biochemical signals, is
essential for various physiological processes such as the conscious sensations of touch and …

Activation of mechanosensitive ion channels underlies a variety of fundamental
physiological processes that require sensation of mechanical force. Different …

Mechanotransduction plays a crucial role in vascular biology. One example of this is the
local regulation of vascular resistance via flow-mediated dilation (FMD). Impairment of this …

A major challenge in neuroscience is to reliably activate individual neurons, particularly
those in deeper brain regions. Current optogenetic approaches require invasive surgical …

Focused ultrasound has been shown to stimulate excitable cells, but the biophysical
mechanisms behind this phenomenon remain poorly understood. To provide additional …

Recent rapid progress in the field of mechanobiology has been driven by novel emerging
tools and methodologies and growing interest from different scientific disciplines. Specific …

TRP channels of the transient receptor potential ion channel superfamily play an important
role in a wide variety of mechanosensory processes, including touch sensation, pain, blood …

Athletic performance relies on tendons, which enable movement by transferring forces from
muscles to the skeleton. Yet, how load-bearing structures in tendons sense and adapt to …

Transduction of mechanical stimuli by receptor cells is essential for senses such as hearing,
touch and pain,,,. Ion channels have a role in neuronal mechanotransduction in …