Pseudomonas aeruginosa is an opportunistic pathogen causing acute and chronic
infections, especially in immunocompromised patients. Its remarkable adaptability and …

Structural biology is experiencing a paradigm shift from targeted structural determination to
structure-guided discovery of previously uncharacterized bioentities. We employed …

Type IV pili (T4Ps) are abundant in many bacterial and archaeal species, where they play
important roles in both surface sensing and twitching motility, with implications for adhesion …

Numerous bacteria naturally occur within spatially organised, multicellular communities
called biofilms. Moreover, most bacterial infections proceed with biofilm formation, posing …

Pseudomonas aeruginosa is one of the most common nosocomial pathogens worldwide,
known for its virulence, drug resistance, and elaborate sensor-response network. The …

The ability of bacteria to interact with and respond to their environment is crucial to their
lifestyle and survival. Bacterial cells routinely need to engage with extracellular target …

Biofilms, which consist of microorganisms enclosed in an extracellular polymeric material
(EPS), hold immense importance in the fields of environmental research, industry, and …

Cannulae are tubular protein filaments that accumulate on the extracellular surface of the
hyperthermophilic archaeon Pyrodictium abyssi during cell division. Cannulae have been …

The emergence of multidrug resistance such as Pseudomonas aeruginosa is due to the
misuse of antibiotics. This has become a significant health concern and calls for the …