Heterocycles in breast cancer treatment: the use of pyrazole derivatives

S Ardevines, E Marqués-López… - Current Medicinal …, 2023 - ingentaconnect.com
Among the aromatic heterocycle rings, pyrazole–a five-membered ring with two adjacent
nitrogen atoms in its structure has been postulated as a potent candidate in the …

Preparation and Application of High-Efficiency, Antibacterial, and Antiviral PET–PTHP Fibers

X He, P Shi, T Wu, B Yu, H Cong… - ACS Applied Materials & …, 2023 - ACS Publications
Transmission through the respiratory tract is one of the most important ways for bacteria and
viruses to infect the human body; the use of high-performance antibacterial and antiviral …

Straightforward synthesis, antiproliferative screening, and density functional theory study of some pyrazolylpyrimidine derivatives

KNM Halim, SA Rizk, MA El‐Hashash… - Journal of …, 2021 - Wiley Online Library
Tetrahydropyrimidinone derivative was synthesized through one‐pot three components
condensation of 1, 3‐diphenylpyrazole‐4‐carbaldehyde with pentan‐2, 4‐dione and urea …

Synthesis, DFT, and eco-friendly insecticidal activity of some N-heterocycles derived from 4-((2-oxo-1, 2-dihydroquinolin-3-yl) methylene)-2-phenyloxazol-5 (4H)-one

EA Ghareeb, NFH Mahmoud, EA El-Bordany… - Bioorganic …, 2021 - Elsevier
A new series of nitrogen heterocycles encompassing a quinoline scaffold such as
imidazolone, benzimidazole, triazinone, triazole, and thiazole derivatives was synthesized …

Synthesis, antiproliferative activity, and molecular docking of some N‐heterocycles bearing a pyrazole scaffold against liver and breast tumors

SK Ramadan, AK El‐Ziaty, RS Ali - Journal of Heterocyclic …, 2021 - Wiley Online Library
A new series of some 1, 3‐diphenylpyrazole‐based heterocycles were constructed from 2‐
cyano‐3‐(1, 3‐diphenyl‐1 H‐pyrazol‐4‐yl) propenoyl chloride (1). The titled acid chloride …

New potential fungicides pyrazole-based heterocycles derived from 2-cyano-3-(1,3-diphenyl-1H-pyrazol-4-yl) acryloyl isothiocyanate

SK Ramadan, NA Ibrahim, SA El-Kaed… - Journal of Sulfur …, 2021 - Taylor & Francis
New series of pyrazole-based heterocyclic systems were synthesized using 2-
cyanopropenoyl isothiocyanate derivative as an intermediate through treating with some …

Synthesis and antioxidant evaluation of some heterocyclic candidates from 3-(1,3-diphenyl-1H-pyrazol-4-yl)-2-(4-oxo-4H-benzo[d][1,3]oxazin-2-yl)propenonitrile

SK Ramadan, AK El-Ziaty… - Synthetic Communications, 2021 - Taylor & Francis
A new series of quinazoline derivatives bearing a 1, 3-diphenylpyrazole core was
synthesized starting from 3-(1, 3-diphenyl-1 H-pyrazol-4-yl)-2-(4-oxo-4 H-benzo [d][1, 3] …

Efficient synthesis and evaluation of antiviral and antitumor activity of novel 3-phosphonylated thiazolo[3,2-a]oxopyrimidines

AA Babushkina, AV Dogadina, DM Egorov… - Medicinal Chemistry …, 2021 - Springer
A series of 3-phosphonylated thiazolo [3, 2-a] oxopyrimidines 3a-k was synthesized for the
first time by the reactions of chloroethynylphosphonates with 5, 6-disubstituted 2-thiouracils …

Synthesis and biological activity on IBD virus of diverse heterocyclic systems derived from 2-cyano-N'-((2-oxo-1,2-dihydroquinolin-3-yl)methylene)acetohydrazide

MM Kaddah, ARI Morsy, AA Fahmi… - Synthetic …, 2021 - Taylor & Francis
Abstract A 2-cyano-N'-((2-oxo-1, 2-dihydroquinolin-3-yl) methylene) ethanohydrazide (3)
was synthesized in 87% yield via condensation of 3-formyl-2-oxoquinoline (1) with 2 …

Synthesis, characterization, computational chemical studies and antiproliferative activity of some heterocyclic systems derived from 3-(3-(1,3-diphenyl-1H-pyrazol-4-yl)acryloyl)-2 …

MM Kaddah, AA Fahmi, MM Kamel… - Synthetic …, 2021 - Taylor & Francis
Abstract The key material, 3-(3-(1, 3-diphenyl-1 H-pyrazol-4-yl) acryloyl)-2 H-chromen-2-one
(3) was synthesized and its behavior toward malononitrile, hydrazine, thiourea …