Apolipoprotein D (apoD) is a 29-kDa glycoprotein that is primarily associated with high
density lipoproteins in human plasma. It is an atypical apolipoprotein and, based on its …

Glucocorticoid effects on the human trabecular meshwork can be used as a model system in
which to study glaucomatous damage to the trabecular meshwork. One of the most important …

Glaucoma is a major cause of blindness and is characterized by progressive degeneration
of the optic nerve and is usually associated with elevated intraocular pressure. Analyses of …

Abstract A glaucoma locus, GLC1A, was identified previously on chromosome 1q. A gene
within this locus (encoding the protein myocilin) subsequently was shown to harbor …

Background A substantial proportion of cases of glaucoma have a genetic basis. Mutations
causing glaucoma have been identified in the chromosome 1 open-angle glaucoma gene …

Glaucoma, a progressive degenerative condition that results in the death of retinal ganglion
cells, is one of the leading causes of blindness, affecting millions worldwide. The …

Apolipoprotein D is a chordate gene early originated in the Lipocalin protein family. Among
other features, regulation of its expression in a wide variety of disease conditions in humans …

purpose. To characterize the gene expression pattern in the human trabecular meshwork
(TM) and identify candidate genes for glaucoma by expressed sequence tag (EST) analysis …

A group of cDNAs isolated from a subtractive ciliary body library of a normal human eye
donor revealed 100% identity with TIGR a candidate gene responsible for juvenile open …

The discovery in the human ocular ciliary body of glaucoma-associated genes (ie, MYOC,
CYP1B1), neuroendocrine processing enzymes, neuroendocrine peptides, steroid …