One of the major impediments to drug development is low aqueous solubility and thus poor
bioavailability, which leads to insufficient clinical utility. Around 70–80% of drugs in the …

An increasing number of people worldwide are affected by eye diseases, eventually leading
to visual impairment or complete blindness. Conventional treatment involves the use of eye …

Blindness and impaired vision are considered as the most troublesome health conditions
leading to significant socioeconomic strains. The current study focuses on development of …

The development of efficient therapies for ocular diseases remains a significant challenge
because of the static and dynamic barriers in the eye. A variety of pharmaceutical strategies …

Eyes are directly exposed to the outer environment and susceptible to infections, leading to
various ocular disorders. Local medication is preferred to treat eye diseases due to its …

Glaucoma is considered to be one of the biggest health problems in the world. It is the main
cause of preventable blindness due to its asymptomatic nature in the early stages on the …

The most common route of administration of ophthalmic drugs is the topical route because it
is convenient, non-invasive, and accessible to all patients. Unfortunately, drugs …

Eyesight is one of the most well-deserved blessings, amid all the five senses in the human
body. It captures the raw signals from the outside world to create detailed visual images …

Purpose The present study was designed to study the gentamycin (GTM)-loaded stimulus-
responsive chitosan nanoparticles to treat bacterial conjunctivitis. Methods GTM-loaded …

The present study was designed to develop dorzolamide HCl (DRZ) loaded cationic
nanoemulsions (CNEs) for enhanced ocular delivery. CNEs were prepared employing high …