Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications

CD Spicer, C Jumeaux, B Gupta… - Chemical Society …, 2018 - pubs.rsc.org
Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …

Gold nanoparticles (GNPs) in biomedical and clinical applications: A review

MI Anik, N Mahmud, A Al Masud, M Hasan - Nano Select, 2022 - Wiley Online Library
Gold nanoparticles (GNPs) have been extensively used in various applications ranging from
environmental detection to biomedical applications. Due to their unique characteristics such …

Nanoparticles and targeted drug delivery in cancer therapy

B Bahrami, M Hojjat-Farsangi, H Mohammadi… - Immunology letters, 2017 - Elsevier
Surgery, chemotherapy, radiotherapy, and hormone therapy are the main common anti-
tumor therapeutic approaches. However, the non-specific targeting of cancer cells has made …

Cell-penetrating peptides (CPPs): An overview of applications for improving the potential of nanotherapeutics

K Desale, K Kuche, S Jain - Biomaterials Science, 2021 - pubs.rsc.org
In the field of nanotherapeutics, gaining cellular entry into the cytoplasm of the target cell
continues to be an ultimate challenge. There are many physicochemical factors such as …

Toxicological behavior of gold nanoparticles on various models: influence of physicochemical properties and other factors

OB Adewale, H Davids… - International journal of …, 2019 - journals.sagepub.com
Potential applications of gold nanoparticles in biomedicine have increasingly been reported
on account of the ease of synthesis, bioinert characteristics, optical properties, chemical …

Escaping the endosome: assessing cellular trafficking mechanisms of non-viral vehicles

E Xu, WM Saltzman, AS Piotrowski-Daspit - Journal of Controlled Release, 2021 - Elsevier
Non-viral vehicles hold therapeutic promise in advancing the delivery of a variety of cargos
in vitro and in vivo, including small molecule drugs, biologics, and especially nucleic acids …

Co-delivery of curcumin and Bcl-2 siRNA by PAMAM dendrimers for enhancement of the therapeutic efficacy in HeLa cancer cells

M Ghaffari, G Dehghan, B Baradaran… - Colloids and Surfaces B …, 2020 - Elsevier
Co-delivery of therapeutic agents and small interfering RNA (siRNA) can be achieved by a
suitable nanovehicle. In this work, the solubility and bioavailability of curcumin (Cur) were …

Cell-penetrating peptides: strategies for anticancer treatment

D Raucher, JS Ryu - Trends in molecular medicine, 2015 - cell.com
Cell-penetrating peptides (CPP) provide an efficient strategy for the intracellular delivery of
bioactive molecules in various biomedical applications. This review focuses on recent …

Peptide-functionalized gold nanoparticles: versatile biomaterials for diagnostic and therapeutic applications

J Zong, SL Cobb, NR Cameron - Biomaterials science, 2017 - pubs.rsc.org
Colloidal gold solutions have been used for centuries in a wide variety of applications
including staining glass and in the colouring of ceramics. More recently, gold nanoparticles …

Metal-based nanoparticle in cancer treatment: lessons learned and challenges

A Hheidari, J Mohammadi, M Ghodousi… - … in Bioengineering and …, 2024 - frontiersin.org
Cancer, being one of the deadliest diseases, poses significant challenges despite the
existence of traditional treatment approaches. This has led to a growing demand for …