Chronic kidney disease as oxidative stress-and inflammatory-mediated cardiovascular disease

A Podkowińska, D Formanowicz - Antioxidants, 2020 - mdpi.com
Generating reactive oxygen species (ROS) is necessary for both physiology and pathology.
An imbalance between endogenous oxidants and antioxidants causes oxidative stress …

The effect of chronic kidney disease on lipid metabolism

N Dincer, T Dagel, B Afsar, A Covic, A Ortiz… - … Urology and Nephrology, 2019 - Springer
The major cause of death among chronic kidney disease patients is cardiovascular
diseases. Cardiovascular and kidney disease are interrelated and increase the severity of …

The sodium–glucose co-transporter 2 inhibitor empagliflozin attenuates cardiac fibrosis and improves ventricular hemodynamics in hypertensive heart failure rats

HC Lee, YL Shiou, SJ Jhuo, CY Chang, PL Liu… - Cardiovascular …, 2019 - Springer
Background Sodium glucose co-transporter 2 inhibitor (SGLT2i), a new class of anti-diabetic
drugs acting on inhibiting glucose resorption by kidneys, is shown beneficial in reduction of …

Mechanisms and modulation of oxidative/nitrative stress in type 4 cardio-renal syndrome and renal sarcopenia

M Sárközy, ZZA Kovács, MG Kovács, R Gáspár… - Frontiers in …, 2018 - frontiersin.org
Chronic kidney disease (CKD) is a public health problem and a recognized risk factor for
cardiovascular diseases (CVD). CKD could amplify the progression of chronic heart failure …

Sudden cardiac death in dialysis: arrhythmic mechanisms and the value of non-invasive electrophysiology

D Poulikakos, K Hnatkova, S Skampardoni… - Frontiers in …, 2019 - frontiersin.org
Sudden Cardiac Death (SCD) is the leading cause of cardiovascular death in dialysis
patients. This review discusses potential underlying arrhythmic mechanisms of SCD in the …

Morphological and functional characteristics of animal models of myocardial fibrosis induced by pressure overload

Y Ding, Y Wang, Q Jia, X Wang, Y Lu… - International journal …, 2020 - Wiley Online Library
Myocardial fibrosis is characterized by excessive deposition of myocardial interstitial
collagen, abnormal distribution, and excessive proliferation of fibroblasts. According to the …

[HTML][HTML] Inhibition of cartilage acidic protein 1 reduces ultraviolet B irradiation induced-apoptosis through P38 mitogen-activated protein kinase and jun amino-terminal …

Y Ji, X Rong, D Li, L Cai, J Rao, Y Lu - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Ultraviolet B (UVB) irradiation can easily induce apoptosis in human lens
epithelial cells (HLECs) and further lead to various eye diseases including cataract. Here for …

UVB induces apoptosis via downregulation of CALML3-dependent JNK1/2 and ERK1/2 pathways in cataract

Y Jia, Q Qin, CP Fang, W Shen… - International …, 2018 - spandidos-publications.com
The aim of the current study was to understand the mechanisms of apoptosis occurring in
cultured human lens epithelial cells (HLECs) following ultraviolet B (UVB) irradiation. The …

The role of electronegative low-density lipoprotein in cardiovascular diseases and its therapeutic implications

S Akyol, J Lu, O Akyol, F Akcay, F Armutcu… - Trends in …, 2017 - Elsevier
Cardiovascular disease (CVD) is a health problem of great concern to both the public and
medical authorities. Low-density lipoprotein (LDL) has been reported to play an important …

Effects of repetitive diet-induced fluctuations in plasma phosphorus on vascular calcification and inflammation in rats with early-stage chronic kidney disease

M Tani, S Tanaka, K Takamiya, M Sakaue… - Journal of Clinical …, 2020 - jstage.jst.go.jp
抄録 Cardiovascular disease is a major cause of death among hemodialysis patients.
Hyperphosphatemia induces cardiovascular disease through vascular endothelial …