Bioactive calcium phosphate-based composites for bone regeneration

M Tavoni, M Dapporto, A Tampieri, S Sprio - Journal of Composites …, 2021 - mdpi.com
Calcium phosphates (CaPs) are widely accepted biomaterials able to promote the
regeneration of bone tissue. However, the regeneration of critical-sized bone defects has …

Nanostructured biomaterials for bone regeneration

JG Lyons, MA Plantz, WK Hsu, EL Hsu… - … in Bioengineering and …, 2020 - frontiersin.org
This review article addresses the various aspects of nano-biomaterials used in or being
pursued for the purpose of promoting bone regeneration. In the last decade, significant …

Bioinspired highly anisotropic, ultrastrong and stiff, and osteoconductive mineralized wood hydrogel composites for bone repair

X Wang, J Fang, W Zhu, C Zhong, D Ye… - Advanced Functional …, 2021 - Wiley Online Library
Anisotropic hydrogels mimicking the biological tissues with directional functions play
essential roles in damage‐tolerance, cell guidance and mass transport. However …

A review of biomimetic and biodegradable magnetic scaffolds for bone tissue engineering and oncology

G Paltanea, V Manescu, I Antoniac, A Antoniac… - International Journal of …, 2023 - mdpi.com
Bone defects characterized by limited regenerative properties are considered a priority in
surgical practice, as they are associated with reduced quality of life and high costs. In bone …

Scaffold-based 3D cellular models mimicking the heterogeneity of osteosarcoma stem cell niche

G Bassi, S Panseri, SM Dozio, M Sandri… - Scientific Reports, 2020 - nature.com
The failure of the osteosarcoma conventional therapies leads to the growing need for novel
therapeutic strategies. The lack of specificity for the Cancer Stem Cells (CSCs) population …

Design strategies and biomimetic approaches for calcium phosphate scaffolds in bone tissue regeneration

F Pupilli, A Ruffini, M Dapporto, M Tavoni, A Tampieri… - Biomimetics, 2022 - mdpi.com
Bone is a complex biologic tissue, which is extremely relevant for various physiological
functions, in addition to movement, organ protection, and weight bearing. The repair of …

Bone regeneration in load-bearing segmental defects, guided by biomorphic, hierarchically structured apatitic scaffold

E Kon, F Salamanna, G Filardo, B Di Matteo… - … in Bioengineering and …, 2021 - frontiersin.org
The regeneration of load-bearing segmental bone defects remains a significant clinical
problem in orthopedics, mainly due to the lack of scaffolds with composition and 3D porous …

Bone-like ceramic scaffolds designed with bioinspired porosity induce a different stem cell response

S Panseri, M Montesi, D Hautcoeur, SM Dozio… - Journal of Materials …, 2021 - Springer
Biomaterial science increasingly seeks more biomimetic scaffolds that functionally augment
the native bone tissue. In this paper, a new concept of a structural scaffold design is …

Zein/gelatin/nanohydroxyapatite nanofibrous scaffolds are biocompatible and promote osteogenic differentiation of human periodontal ligament stem cells

Q Ou, Y Miao, F Yang, X Lin, LM Zhang… - Biomaterials science, 2019 - pubs.rsc.org
In bone tissue engineering, it is important for biomaterials to promote the osteogenic
differentiation of stem cells to achieve tissue regeneration. Therefore, it is critical to develop …

Surface phenomena enhancing the antibacterial and osteogenic ability of nanocrystalline hydroxyapatite, activated by multiple-ion doping

S Sprio, L Preti, M Montesi, S Panseri… - ACS Biomaterials …, 2019 - ACS Publications
The present work describes a novel nanocrystalline, multidoped hydroxyapatite featuring
excellent eukaryotic versus prokaryotic cell selectivity, attested by excellent osteoinductive …